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TL;DR: In 792 people with stable multiple sclerosis, a blood marker of nerve damage more often placed them in an older age band than their actual age, compared with 302 people without MS. The gap was larger in people with more disability or progressive MS, but…
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TL;DR: A 2026 preprint in medRxiv found that brain-derived p-tau217%, a blood marker designed to isolate central nervous system tau, classified Alzheimer disease pathology better than standard plasma p-tau217 in several Alzheimer cohorts. Key Findings CNS-sele…
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TL;DR: A 2026 preprint in medRxiv reported that serum myelin oligodendrocyte glycoprotein (MOG) protein was higher in multiple sclerosis than controls and higher during clinical relapse than remission. Key Findings 20.5 pg/ml higher: Serum MOG protein was high…
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TL;DR: A 2026 study in Translational Psychiatry found that three different plasma p-tau217 assays separated Alzheimer’s dementia from controls and frontotemporal degeneration with excellent accuracy, shifting the test from whether the marker works to which pla…
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TL;DR: A 2026 systematic review and meta-analysis in Molecular Neurobiology found that plasma phosphorylated tau 217 (p-tau217), a blood marker of Alzheimer-linked tau pathology, identified biomarker-defined Alzheimer’s disease with pooled sensitivity of 85.4%…
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