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Adding transcranial alternating current stimulation (tACS) to antidepressant treatment improves depression symptoms more effectively than using antidepressants alone. Highlights: Enhanced Efficacy: tACS combined with antidepressants significantly reduces depre…
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Probiotics may help improve sexual function and reduce depression severity in women treated with SSRIs. Highlights: Depression Prevalence: Approximately 5% of all adults will experience depressive disorder, often accompanied by reduced sexual desire and dysfun…
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Researchers conducted a comprehensive analysis comparing 20 antidepressants to identify the most effective options for preventing relapse in patients with major depressive disorder (MDD). Their findings suggest desvenlafaxine, paroxetine, venlafaxine and vorti…
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The European Medicines Agency (EMA) has updated its guidance on clinical trials for new depression treatments, with the goals of harmonizing standards across the EU and facilitating development of improved therapies. Key Facts: Depression is a highly disabling…
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Kava kava, an herbal supplement made from the root of Piper methysticum, has gained popularity as an alternative treatment for anxiety and insomnia. A recent systematic review and meta-analysis re-examined kava kava’s effectiveness and safety for anxiety disor…
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The novel combination drug dextromethorphan-bupropion (Auvelity) was recently approved by the FDA as an oral antidepressant that works rapidly to treat major depressive disorder in adults. This new medication represents an exciting development for depression t…
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Depression affects over 300 million people globally. Current treatments have limited efficacy for many patients. Exciting new research highlights the potential of allopregnanolone agonists like brexanolone and zuranolone as more targeted, rapid-acting antidepr…
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Deep brain stimulation (DBS), a surgical procedure that implants electrodes in the brain to deliver electrical stimulation, may offer hope for people with severe depression that has not responded to multiple treatments. However, larger and more rigorous studie…
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Depression is one of the most common and burdensome mental health disorders globally, affecting over 300 million people. While antidepressant medications can help many patients recover, up to a third do not respond adequately to first-line treatments. This has…
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