epilepsy

Necrostatin-1: A Necroptosis Inhibitor to Treat Neurological Disorders (2024 Research)

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Necrostatin-1, an inhibitor of necroptosis, exhibits significant neuroprotective effects and potential therapeutic applications in various neurological disorders by modulating cell death pathways, inflammation, and reactive oxygen species. Highlights: Mechanism of Action: Necrostatin-1 specifically inhibits receptor-interacting protein 1 (RIP1), preventing necroptosis and other cell death pathways, including apoptosis and ferroptosis. Neuroprotective Role: It shows promise in …

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Targeting the Gut Microbiome to Treat Epilepsy & Seizures: Future Potential (2024 Research)

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Gut microbiota may influence epilepsy, but the exact mechanisms and involved microbiota are unclear, with potential treatments including ketogenic diets, probiotics, and fecal microbiota transplants being explored. Highlights: Approximately 33% of epilepsy patients are resistant to all antiseizure medications, with the role of gut microbiota in epilepsy being increasingly evident. The gut-brain axis, involving neuroendocrine, …

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Transcranial Ultrasound Stimulation: Benefits & Future Applications

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Our brains contain around 100 billion neurons communicating through an intricate web of connections. This complex circuitry controls everything we think, feel, and do. But sometimes things can go wrong, leading to neurological disorders like epilepsy, Parkinson’s disease, depression and Alzheimer’s. An exciting new approach called transcranial ultrasound stimulation (TUS) is showing great promise as …

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New Epilepsy Treatments in Development (2023): Neuromodulation, CBD, Gene Therapy

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Epilepsy impacts millions of people worldwide. While medications have been the mainstay of treatment, one-third of patients continue to have seizures despite available drugs. This highlights the need for innovative therapies. Recent years have seen exciting developments that bring new promise for improved seizure control. Key Facts: Epilepsy is a neurological disorder characterized by recurrent, …

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