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gut-brain axis

Drugs & MedicationsMay 14, 2026

Intestinal Epithelial Serotonin Reduced Anxiety and Depression-Like Behavior via Vagus in Mice; In Utero SSRI Linked to Infant Constipation

TL;DR: A 2024 Gastroenterology study found that intestinal epithelial serotonin reduced anxiety- and depression-like behavior in mice through vagal signaling, while prenatal SSRI exposure in a human cohort predicted infant functional constipation independent o…

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Health & WellnessMay 4, 2026

Early Life Stress Rewired Gut Nerves and Visceral Pain Pathways

Early Stress Rewired the Gut’s Nerves, Not Just the Brain TL;DR: Early life stress produced lasting gut pain and motility changes through enteric and sympathetic nerve pathways, with pediatric cohort data pointing in the same direction. Key Findings Maternal s…

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Intestinal Epithelial Serotonin Reduced Anxiety and Depression-Like Behavior via Vagus in Mice; In Utero SSRI Linked to Infant Constipation

Early Life Stress Rewired Gut Nerves and Visceral Pain Pathways

The findings. The context. The caveats.