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TL;DR: A 2025 study in PNAS found that sLC35F2 emerged as the high-specificity transporter for queuine and queuosine, linking gut-derived micronutrients to tRNA modification and the cell’s protein-translation machinery. Key Findings 30-year transporter mystery…
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TL;DR: A 2025 study in Journal of the American Chemical Society found that a depression-linked gut bacterium now has a concrete inflammatory mechanism: Morganella morganii can make unusual phospholipids that activate TLR2/TLR1 and drive IL-6. Key Findings Morg…
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TL;DR: A 2026 Current Biology study found that bacterial polysaccharides, including peptidoglycan from Gram-positive bacteria, activated the C. elegans NSM enteric sensory neuron and shifted feeding and movement behavior through acid-sensing ion channels. Key…
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Obesity and Depression Share Five Converging Biological Pathways Obesity and depression represent two of the world’s fastest-growing epidemics. By 2030, over 1 billion people will have obesity, while depression will affect more than 350 million. Yet they are r…
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