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TL;DR: A 2026 Nature Communications paper introduced EmulatRx, a multi-agent AI framework that used real-world clinical data to help design target-trial-emulation workflows for acute and chronic diseases, including Alzheimer disease and Parkinson disease examp…
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TL;DR: A 2026 protocol in JMIR Research Protocols describes EXCEL-PD, a randomized trial testing whether 26 weeks of virtually supervised home endurance and resistance exercise is feasible, safe, and biologically informative for people with Parkinson disease.…
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TL;DR: A 2026 medRxiv preprint reported that peripheral blood RNA sequencing separated Parkinson disease from healthy controls and isolated REM sleep behavior disorder more clearly than it separated isolated REM sleep behavior disorder from controls. Key Findi…
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TL;DR: A 2026 review in Translational Neuroscience summarizes why PINK1 and parkin, two genes linked to early-onset parkinsonism, keep pointing researchers back to mitophagy and autophagy as Parkinson disease mechanisms. Key Findings 18 PARK loci noted: The re…
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