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treatment-resistant depression

AntidepressantsMay 6, 2026

Ketamine Effective for Treatment-Resistant Depression: No Added Benefit from Music

TL;DR: A 2026 randomized trial in The British Journal of Psychiatry found 6 ketamine infusions improved severe treatment-resistant depression, but curated music added no measurable benefit; higher mystical-experience scores still predicted the next session’s d…

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AntidepressantsMay 3, 2026

Ketamine Restored Reward Bias in Depression and Stressed Rats

Ketamine Restored Reward Bias Across Species TL;DR: Ketamine restored reward-learning bias in both treatment-resistant depression and chronically stressed rats while leaving basic discrimination unchanged. Key Findings Reward bias increased: Ketamine significa…

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Ketamine Effective for Treatment-Resistant Depression: No Added Benefit from Music

Ketamine Restored Reward Bias in Depression and Stressed Rats

The findings. The context. The caveats.