Chai-Hu-Jia-Long-Gu-Mu-Li-Tang for Depression Treatment: Untapped Potential of Traditional Chinese Herbs?

Researchers have uncovered new evidence that a traditional Chinese herbal medicine may be a safe, effective option for treating depression. The formula, known as Chaihu-jia-Longgu-Muli-tang (CLM) also phrased “Chai Hu Jia Long Gu Mu Li Tang,” outperformed standard antidepressants in clinical trials and appears to work via multiple mechanisms in the brain. Key findings: In …

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Adding Lithium to Drinking Water for Suicide Prevention: Controversial Public Health Proposal

Suicide is a major global public health problem, accounting for over 800,000 deaths worldwide each year. Lithium, a mood stabilizing medication, has been proposed as a novel population-level suicide prevention strategy through supplementation of trace doses into the public drinking water supply. This controversial idea has sparked much debate around its ethics, risks, benefits and …

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Fluoride Exposure During Brain Development: IQ Decline & Neurotoxic Effects?

A new review of research finds strong evidence that fluoride exposure, especially during fetal development and infancy, can lead to decreased IQ and other neurotoxic effects. While fluoride may help prevent dental cavities when applied topically, ingesting elevated levels early in life appears to pose risks to long-term brain health. Key facts: Multiple recent studies …

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Post-COVID Lung Damage Linked to Anxiety & Depression

A new study reveals important connections between lingering lung damage after COVID-19 and mental health issues like anxiety and depression. The research also demonstrates that simple at-home breathing exercises can improve both lung function and mood. Key facts: 1 in 3 patients in the study still had abnormal lung function 2 months after moderate COVID-19 …

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High Rates of Pineal Gland Calcification & Possible Health Effects

Pineal gland calcification, the buildup of calcium deposits in the pineal gland, is surprisingly common, affecting over 60% of the population according to a new meta-analysis. This concerning condition can disrupt proper pineal gland functioning and melatonin secretion, potentially contributing to an array of health issues. Key Facts: The pineal gland regulates circadian rhythms through …

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Microplastics & Health Effects in Humans: Physiological Damage & Disease?

Microplastics, the tiny plastic fragments less than 5mm in size, are increasingly being found everywhere – in the oceans, freshwater systems, soil, air, and even in our food. As these tiny plastic pieces spread unabated into the environment, scientists are concerned about their effects on human health. Key facts: Over 6,000,000 tons of microplastics are …

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Medications & Drugs for Borderline Personality Disorder: Do Effective Treatments Exist?

Borderline personality disorder (BPD) is a common and debilitating mental health condition, yet medication options remain limited according to a new systematic review published in CNS Drugs. The study found minimal evidence supporting the benefits of medication for BPD beyond some improvement in individual symptoms. No drugs have been approved for BPD and there is …

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Celecoxib for Depression: Targeting Inflammation via COX-2 (2023 Research Update)

Mood disorders like major depression and bipolar disorder affect millions worldwide. Existing treatments often fall short, highlighting the need for better options. An emerging possibility is anti-inflammatory drugs like celecoxib that may target the immune system abnormalities linked to these conditions. A new comprehensive review suggests celecoxib holds promise as an add-on treatment for major …

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CGRP Antibodies & Migraine Prevention: Targeting Calcitonin Gene-Related Peptide

A new network meta-analysis published in Frontiers in Pharmacology provides important insights into the relative efficacy and safety of monoclonal antibodies targeting calcitonin gene-related peptide (CGRP) for migraine prevention. This comprehensive analysis compares four CGRP monoclonal antibodies – eptinezumab, erenumab, fremanezumab, and galcanezumab – and sheds light on which ones are most effective for reducing …

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Solriamfetol for ADHD in Adults: Norepinephrine-Dopamine Reuptake Inhibitor

Attention-deficit/hyperactivity disorder (ADHD), long thought of as a childhood condition, is increasingly recognized as a disorder that can persist into adulthood. Up to 60% of children with ADHD continue to experience symptoms as adults. Yet treatment options specifically tested and approved for adult ADHD remain limited. A new study published this month in the Journal …

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