Amphetamine Sensitization Alters Brain’s Reward Circuits in Humans (Study)

Researchers have found that repeated low doses of amphetamine can alter reward and motivation circuits in the human brain. The changes mirror what is seen in addiction and schizophrenia. Key Facts: Healthy volunteers received 4 doses of a low 20mg dose of amphetamine or placebo, spaced 2 days apart. Those getting amphetamine showed enhanced subjective …

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Brain Tumors Linked to Psychiatric Symptoms in ~27% of Patients

Brain tumors can take a major toll on mental health. New research provides important insights into the psychiatric symptoms that often accompany these devastating diseases. Key Facts: Around 27% of brain tumor patients experience psychiatric symptoms like depression and anxiety. These frequently arise before diagnosis. Depressive symptoms are most common, affecting 24% of brain tumor …

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Ultraprocessed Foods & Health Risks: Dangers of Junk Food (Study)

Eating large amounts of ultra-processed foods may increase the risk of obesity, heart disease, stroke, depression, and early death, according to a new systematic review and meta-analysis. Key Facts: Ultra-processed foods are industrial formulations made with ingredients extracted from foods or synthesized in labs. Examples include chips, soft drinks, instant noodles, chicken nuggets, and frozen …

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Curcumin Health Benefits (2023): Latest Research & Therapeutic Potential

Curcumin is a natural compound found in turmeric that has been used in traditional medicine for centuries. Recent research has confirmed curcumin’s wide-ranging health benefits, from reducing inflammation to protecting against neurodegenerative diseases. Key Facts: Curcumin is the main active compound in turmeric and has powerful antioxidant and anti-inflammatory effects. Research shows curcumin can help …

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Male vs. Female Brains: Sex Differences in Structure, Function, Psychiatric Disorders

While male and female brains are far more alike than different, research over the past few decades has revealed some subtle but meaningful variations. These differences likely stem from a complex interplay of biological factors, experiences, societal influences, and more. Key Facts: On average, male brains are about 10% larger than female brains. But when …

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Modafinil & Sleep Homeostasis: Effects Determined By COMT Gene Variants

New research reveals that the wake-promoting drug modafinil affects markers of sleep homeostasis differently depending on a person’s genetics. Key facts: Modafinil improved sustained attention in people with a certain gene variant but not others after sleep deprivation. Modafinil reduced sleepiness and theta brain waves during wakefulness regardless of genetics. Modafinil did not reduce slow …

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Higher Intelligence (IQ) in Youth Linked to Lower Depression as an Adult (Age 50)

A recent longitudinal study provides new insight into the association between intelligence in adolescence and mental health outcomes in middle age. The research indicates that higher intelligence in youth is linked to a lower risk of some common mental health issues at age 50, but a greater likelihood of receiving a depression diagnosis. Key facts: …

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Genetic DNA Mutations in Human Population: Simulation Suggests Beneficial Genes Offset Decline

Humans and other complex organisms face a constant barrage of new harmful genetic mutations, yet somehow manage to persist and evolve despite this mutational load. New research reveals how populations can survive this onslaught through a delicate balancing act between bad and good mutations. Key Facts: Each person inherits around 2-10 new harmful mutations from …

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Pesticide Exposure is Neurotoxic: Links to Neurological & Psychiatric Disorders

Pesticides are chemical substances commonly used in agriculture to eliminate pests and enhance crop yields. However, indiscriminate use of pesticides has raised concerns about potential toxicity and adverse health effects in humans. Key Facts: Pesticide exposure is linked to neurological disorders like Parkinson’s disease, Alzheimer’s disease, and psychiatric conditions including depression and suicide. Exposure can …

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Green Coffee Bean Extract (CGA-7) for Weight Loss: Clinical Study Finds Benefits

A new randomized, double-blind, placebo-controlled clinical trial provides evidence that a green coffee bean extract standardized to chlorogenic acids (CGA-7) can help with weight loss in healthy overweight adults. Key facts: CGA-7 supplementation for 12 weeks resulted in significant reductions in body weight, BMI, body fat percentage and fat mass compared to placebo. Improvements were …

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