TL;DR: A 2026 preprint posted on medRxiv reported that resting-state electroencephalography (EEG) neural slowing after stroke tracked secondary thalamic degeneration measured on structural MRI, even though the sampled patients did not have direct thalamic lesions. Key Findings 25 stroke patients: Researchers studied adults at least 3 months after unilateral supratentorial stroke and compared their resting-state …
TL;DR: A 2026 review in International Journal of Molecular Medicine mapped how exercise and fluoxetine overlap in Alzheimer’s disease mechanisms such as mitochondrial quality control, oxidative stress, inflammation, and neuroplasticity, but clinical combination benefits remain unproven. Key Findings Review article, not trial: Wu and Li synthesized mechanistic evidence on exercise and fluoxetine in Alzheimer’s disease …
TL;DR: A 2026 preprint posted on medRxiv reported that larger choroid plexus volume on brain MRI was associated with greater disability in multiple sclerosis and with higher white-matter myo-inositol in progressive MS, but the work has not yet been peer reviewed. Key Findings 88-person imaging sample: Researchers studied 45 people with multiple sclerosis and 43 …
TL;DR: A 2026 case study in International Medical Case Reports Journal described a 42-year-old man whose chronic insomnia improved after celiac disease was diagnosed and treated with a gluten-free diet, but the report cannot prove gluten exposure caused the sleep problem. Key Findings 5 months of insomnia: The patient reported persistent difficulty initiating and maintaining …
TL;DR: A 2026 systematic review and meta-analysis in Brain, Behavior, & Immunity – Health found that adding celecoxib to antidepressants was linked to lower depressive symptom scores in 7 small trials, but the efficacy evidence was rated very low certainty. Key Findings 7 randomized trials: The meta-analysis included 365 adults with major depressive disorder, with …
TL;DR: A 2026 systematic review and meta-analysis in Journal of Alzheimer’s Disease found that choroid plexus volume, an MRI-visible structure involved in cerebrospinal-fluid regulation and immune signaling, was larger in Alzheimer’s disease than in healthy controls. Key Findings Sixteen studies: The review included 16 MRI-based studies covering 2,004 Alzheimer’s disease patients and 883 healthy controls. …
TL;DR: A 2026 study in Nature Communications found that neuropsychiatric disorder risk did not map onto cognition as one general trait. Schizophrenia, bipolar disorder, ADHD, autism, and Alzheimer’s disease showed different genetic links with reaction time, fluid reasoning, crystallized knowledge, and noncognitive educational skills. Key Findings 439,000-person GWAS scale: The crystallized-knowledge genome-wide association study had …
TL;DR: A 2026 systematic review in Future Science OA found early medication evidence for online behavioral addictions, but the 20 included studies were mostly small, male-heavy, and short-term. Key Findings Medication evidence stayed early: The review found small, mixed pharmacotherapy signals across 20 online behavioral addiction studies. Clinical groups stayed small: The 1,016 total participants …
TL;DR: A 2026 real-world study in Journal of Clinical Sleep Medicine found that glucagon-like peptide-1 receptor agonist use was associated with lower 3-year cardiovascular-event risk in adults with obesity and obstructive sleep apnea. Key Findings 18,523 matched pairs: Propensity matching compared GLP-1 receptor agonist users with similar non-users who had obesity and obstructive sleep apnea. …
TL;DR: A 2026 crossover study in Clinical Physiology and Functional Imaging found that adding electrical muscle stimulation to low-intensity resistance exercise improved inhibitory control in young men, while stimulation alone showed a delayed 15-minute benefit. Key Findings 17 young men: Participants completed low-intensity resistance exercise, electrical muscle stimulation alone, and combined low-intensity exercise plus stimulation …
