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Semaglutide is emerging as a wonder drug for management of various metabolic diseases. Originally approved for type 2 diabetes, this glucagon like peptide-1 (GLP-1) receptor agonist is now showing promise for treating obesity, non-alcoholic steatohepatitis (NA…
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Eating large amounts of ultra-processed foods may increase the risk of obesity, heart disease, stroke, depression, and early death, according to a new systematic review and meta-analysis. Key Facts: Ultra-processed foods are industrial formulations made with i…
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A new randomized, double-blind, placebo-controlled clinical trial provides evidence that a green coffee bean extract standardized to chlorogenic acids (CGA-7) can help with weight loss in healthy overweight adults. Key facts: CGA-7 supplementation for 12 weeks…
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A new case-control study reveals an association between obesity, depression, and decreased levels of the protein neuregulin-1 (NRG-1). The research suggests NRG-1 may serve as a biomarker linking depression and obesity. Key facts: Depressive symptoms were more…
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Obesity can lead to impaired learning, memory and cognitive decline, but the underlying mechanisms are not fully understood. A new mouse study reveals how obesity disrupts key signaling pathways in the brain, and shows the potential of two diabetes drugs, sema…
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A new systematic review and meta-analysis suggests that swapping out sugar-sweetened beverages (SSBs) for low- and no-calorie sweetened beverages (LNCSBs) may support modest weight loss and improve certain cardiometabolic factors. The study found that LNCSBs o…
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A new study looked at how having diabetes may impact brain health in Native Americans. The researchers found that the longer someone had diabetes, the more it affected their brain. But other health issues like obesity did not appear to impact the brain as much…
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Our bodies have an internal “clock” that anticipates and prepares for food intake at regular times each day. This was demonstrated in a new scientific study that manipulated meal timing in participants. Key Facts: Participants were given either 2 large meals p…
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Researchers have uncovered novel details about a specific population of brain cells that regulate obesity. Their findings provide increased understanding of the intricate neural circuits controlling energy balance and point to potential new therapeutic targets…
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Obesity has been linked to faster brain aging, but can losing weight turn back the clock? A new study provides compelling evidence that shedding pounds through lifestyle changes may attenuate brain aging. Key facts: Participants lost an average of 5% of body w…
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