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TL;DR: In rats given the chemotherapy drug doxorubicin, which caused memory problems, adding the antipsychotic lurasidone protected memory on maze and object tests. This was a prevention study in male rats, not a treatment for people with “chemo brain.” Key Fi…
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TL;DR: In rats trained to spot a brief flash of light, a drug that blocks one nicotine-type receptor (alpha-7) made them better at telling flash from no flash, even with distractions. Drugs that boosted the same receptor made them worse at high doses. Key Find…
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TL;DR: A 2026 rat study in Neuropsychopharmacology reported that repeated semaglutide treatment reduced cocaine-vs-food choice in male and female rats, supporting further clinical testing for cocaine use disorder rather than proving human benefit. Key Findings…
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TL;DR: A 2026 iScience study found that both humans and rats could report their own timing errors in a 2-second task, but rats made more accurate error-based choices than humans. Key Findings Matched timing task: Researchers compared 34 adults with 16 male Spr…
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TL;DR: A 2026 rat study in Neuropsychopharmacology found that chemogenetically inhibiting a prelimbic cortex to nucleus accumbens core pathway blocked cue-triggered cocaine seeking after cocaine alone, but did not block relapse-like behavior after sequential c…
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