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TL;DR: A 2026 randomized trial in JMIR Mental Health found that a 4-week executive-function training app reduced depression and anxiety symptoms at 12-week follow-up, while a self-guided CBT app mainly improved workplace well-being. Key Findings Workplace app…
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TL;DR: A 2026 study in Journal of Nanobiotechnology found that Angiopep-2-modified natural killer cell extracellular vesicles carried temozolomide across glioblastoma barriers, reduced mouse tumor bioluminescence, and extended median survival in an orthotopic…
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TL;DR: A 2026 preprint in medRxiv used amyloid positron-emission tomography, tau molecular imaging, and structural MRI to build individualized Alzheimer’s disease biomarker axes from ADNI and validate them in OASIS. Key Findings 12,430 ADNI images: The pipelin…
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TL;DR: A 2026 study in Drug and Alcohol Review found that laypeople reported more and better-developed cues for alcohol intoxication than cannabis intoxication, even though most coded cues for both substances were accurate. Key Findings Intoxication-cue sample…
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TL;DR: A 2026 systematic review in BMC Medical Informatics and Decision Making found that AI models using remote-monitoring data were most often studied in Parkinson’s disease, but 56 of 76 prospective studies had high risk of bias. Key Findings 6,668 records…
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TL;DR: A 2026 study in Research on Child and Adolescent Psychopathology followed 951 New Zealand adolescents and found that 5 emotion-regulation profiles tracked different patterns of anxiety, depression, optimism, resilience, and wellbeing over 5 months. Key…
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TL;DR: A 2026 preprint in medRxiv found that the ADAS-Cog-13 cognitive scale detected impairment in older adults with focal epilepsy, but a cutoff of 15 had only modest diagnostic accuracy against an epilepsy-specific neuropsychological standard. Key Findings…
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TL;DR: A 2026 randomized study in The British Journal of Psychiatry found that the experimental 5-HT4 receptor agonist PF-04995274 did not mimic citalopram’s early emotional-bias effects in unmedicated depression, but it was linked with lower depression rating…
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TL;DR: A 2026 study in Psychopharmacology found that low oral THC doses did not meaningfully reduce most subjective or physiological responses when healthy adults retrieved memories of a prior social stress task. Key Findings Low-dose THC groups: Participants…
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TL;DR: A 2026 exploratory study in Translational Psychiatry found blood DNA methylation changes after 25 mg psilocybin in detoxified alcohol use disorder patients, including findings near TLE4 and RASGRP4, but the small trial did not establish a definitive AUD…
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