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TL;DR: A 2026 study in Human Brain Mapping found that full-term neonates already showed stronger structural and functional connectivity between cortical gyri than between sulci, with brain structure-function coupling shifting toward decoupling around 41 weeks…
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TL;DR: A 2026 study in Nature Communications used deep learning, yeast screening, and human brain organoids to identify talarozole and sertaconazole as preclinical candidates that rescued several SURF1-related Leigh syndrome cell and organoid phenotypes. Key F…
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TL;DR: A 2026 pilot trial in PLOS One found that a 7-day chicory-and-green-tea herbal supplement did not improve sleep, quality of life, or objective sleep architecture more than placebo in adults with insomnia. Key Findings Small crossover pilot: The crossove…
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TL;DR: A 2026 preclinical study in the International Journal of Nanomedicine developed human umbilical cord mesenchymal stem cell membrane-coated PLGA nanoparticles to co-deliver doxorubicin and curcumin to glioblastoma models, improving tumor-cell uptake and…
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TL;DR: A 2026 systematic review in The Cerebellum found that deep brain stimulation (DBS) produced modest symptom improvement in selected cerebellar ataxia patients, with dentate nucleus stimulation most common in humans and interposed nucleus stimulation emer…
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TL;DR: A 2026 meta-analysis in Psychological Medicine found that reduced resting-state connectivity between the amygdala and anterior cingulate cortex was the most robust brain-network difference in anxiety disorders. Key Findings 15 datasets: The meta-analysi…
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TL;DR: A 2026 study in Acta Neuropathologica Communications used Boolean-network AI analysis of Alzheimer’s RNA-seq data to identify a 40-gene disease signature and validate CgA-KO/PS19 mice as a model of asymptomatic Alzheimer’s-like resilience. Key Findings…
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TL;DR: A 2026 systematic review and meta-analysis in Lupus found that psychosis affected about 4.5% of adults with systemic lupus erythematosus (SLE), was more common in neuropsychiatric SLE, and tracked most strongly with active immune disease markers rather…
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TL;DR: A 2026 preprint in medRxiv found that head-impact-related magnetoencephalography (MEG) changes in high-school football players were strongest in cortical regions matching specific neurotransmitter and gene-expression maps, especially norepinephrine, nic…
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TL;DR: A 2026 study in Biological Psychiatry: Global Open Science found that systemic low-frequency oscillation (sLFO), a slow whole-body physiology readout usually treated as functional MRI noise, tracked nicotine dependence, cue-induced craving, abstinence,…
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