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TL;DR: A 2026 randomized phase 2b trial in Journal of Clinical Psychopharmacology found that the PDE10A inhibitor MK-8189 did not improve Positive and Negative Syndrome Scale (PANSS) schizophrenia symptom scores more than placebo after 6 weeks, while risperido…
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TL;DR: A 2026 study in Neuropsychopharmacology used CRISPR gene editing in human microglia-like cells and found that several schizophrenia-linked genes changed phagocytosis, cell shape, and immune-transcription programs. Key Findings Schizophrenia-linked micro…
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TL;DR: A 2026 qualitative analysis in PLOS One used 505 ME/CFS memorial entries to map how systemic neglect, clinical dismissal, social isolation, and personal burden appeared in accounts of illness and death. Key Findings 505 memorial entries: The analysis us…
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TL;DR: A 2026 preprint on medRxiv tested suicide-risk vignettes and found that an independent supervisory safety agent detected intervention-level risk far more often than native ChatGPT Health safeguards. Key Findings 224 paired evaluations: Researchers teste…
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TL;DR: A 2026 study in Neurology found that higher autonomic symptom burden in moderate-advanced dementia with Lewy bodies was linked to worse cognitive fluctuations, higher neuropsychiatric burden, and lower caregiver quality of life over time. Key Findings A…
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TL;DR: A longitudinal study in BMC Public Health followed Swedish municipal office workers before and after hybrid work became routine and found improved psychosocial work-experience scores, especially for time pressure, autonomy, leadership access, and women…
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TL;DR: A 2026 meta-analysis in Sleep and Breathing found that GLP-1 drugs, metabolic hormone medications involved in glucose, appetite, and weight regulation, were linked to fewer obstructive sleep apnea breathing events in adults with obesity. Key Findings Sl…
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TL;DR: A 2026 analysis in Journal of Korean Medical Science identified PIK3CG, PRKCD, and TRIM22 as glioblastoma gene markers linked to worse survival and stronger immune-activity signals in IDH-wildtype tumors. Key Findings 12,041-gene screen: Researchers scr…
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TL;DR: A pilot cohort study in JMIR Rehabilitation and Assistive Technologies found that online emotional training after facial palsy surgery improved facial movement, social well-being, and anxiety about as much as in-person therapy in 16 adults. Key Findings…
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TL;DR: A 2026 functional MRI (fMRI) study in Psychological Medicine found that schizophrenia, bipolar disorder, and major depressive disorder shared some thalamus connectivity disruption, but each diagnosis showed a different subcortical network pattern across…
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