Neurobiology of Bipolar Disorder: Genetic & Brain Imaging Links

Bipolar disorder, formerly known as manic depression, is a chronic mental illness characterized by dramatic shifts in mood and energy levels. It affects about 2-4% of the population worldwide. While we still don’t fully understand what causes bipolar disorder, research over the past couple decades has uncovered important clues into the biological mechanisms behind this …

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Bipolar Mania & Brain Activation: Right Ventral PFC & Limbic Dysfunction

Mania is characterized by emotional dysregulation, sleep disturbances, and impaired judgment. Understanding its underlying brain circuitry could lead to improved diagnosis and treatment. Key Facts: Mania involves decreased activity in the right ventral prefrontal cortex (PFC) and increased activity in the left amygdala, left anterior cingulate cortex (ACC), and left basal ganglia. This lateralized limbic …

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Deep Brain Stimulation Side Effects in Parkinsons Disease: Do Benefits Outweigh Risks?

Deep brain stimulation (DBS) is an effective but not perfect therapy. A large new study found that over 4-7 years, a majority of patients experienced adverse events, though most were not severe. Key facts: 86% of 123 DBS patients experienced adverse events over an average 4.7 year follow-up. There was no mortality directly from DBS …

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Deep Brain Stimulation for Treatment-Resistant Depression (TRD): Potential Benefits & Effectiveness Reviewed

Deep brain stimulation (DBS), a surgical procedure that implants electrodes in the brain to deliver electrical stimulation, may offer hope for people with severe depression that has not responded to multiple treatments. However, larger and more rigorous studies are still needed to confirm its benefits and long-term safety. Key Facts: DBS targets areas of the …

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Deep Brain Stimulation for Depression: Determining Optimal Targets & Protocols

Deep brain stimulation (DBS) is an emerging experimental therapy that has shown promise in treating patients with severe, treatment-resistant depression (TRD). Early research indicates DBS may help patients who have failed to respond to medications, psychotherapy, and other interventions. Key facts: DBS involves surgically implanting electrodes in specific brain regions to deliver mild electrical stimulation. …

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Fear of Missing Out (FOMO) & Internet Use: No Clear Link Except Social Media

Researchers conducted a comprehensive meta-analysis exploring the association between fear of missing out (FOMO) and internet use. The analysis integrated 85 studies involving over 55,000 participants. Here are some key facts from the research: The correlation between FOMO and internet use ranged widely, from 0.11 to 0.63 across studies. The FOMO-internet use correlation was similar …

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Behavioral Addiction Treatment: CBT & Antidepressants Most Effective?

Behavioral addictions like internet, sex, and shopping addictions may not be formally recognized as psychiatric conditions, but research shows that treatments can be effective in reducing problematic symptoms. Key Facts: Psychological, pharmacological, and combined treatments all showed robust improvements in global severity and frequency of compulsive behaviors for internet, sex, and shopping addictions. Treatment gains …

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Maladaptive Daydreaming: A New Behavioral Addiction?

Maladaptive daydreaming (MD) is a newly recognized behavioral addiction characterized by excessive absorption in fantasy. Key facts about Maladaptive Daydreaming: It involves compulsive,immersive daydreaming that impairs functioning MD serves as an escape and emotional regulation strategy It shares features with other behavioral addictions like gaming and porn addiction MD can occupy many hours a day …

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Cell Phone Addiction Linked to Anxiety, Depression, Impulsivity, Poor Sleep

A new meta-analysis published in the Journal of Behavioral Addictions explores the relationship between mobile phone addiction (MPA) and mental health issues like anxiety, depression, impulsivity, and poor sleep quality in college students. The analysis, conducted by researchers in China, pooled data from 40 studies involving over 33,000 college students worldwide. Key Takeaways: College students …

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