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TL;DR: A 2026 medRxiv preprint applied the AT(N) framework, an Alzheimer’s disease biomarker system for amyloid, tau, and neurodegeneration, to 84 older adults with focal epilepsy and found that only 32.1% had normal blood biomarkers, while early-onset epileps…
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TL;DR: A 2026 study in Microbiome found that in older adults at metabolic risk, virgin olive oil was linked to better cognitive preservation and richer gut microbiota, while common refined olive oil pointed the other way. Key Findings Metabolic-risk cohort tra…
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TL;DR: A 2026 study in Cell Chemical Biology found that alzheimer’s inflammation may be driven by a specific chemical switch: S-nitrosylation of STING at cysteine 148, which pushed innate immune signaling toward synaptic damage. Key Findings STING carried the…
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TL;DR: A 2026 study in Neurology Open Access found that in 793 dementia-free adults, higher vitamin D levels around age 39 were associated with less tau readout on PET brain imaging about 16 years later, while amyloid beta did not show the same relationship. K…
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TL;DR: A 2026 study in Translational Psychiatry found that three different plasma p-tau217 assays separated Alzheimer’s dementia from controls and frontotemporal degeneration with excellent accuracy, shifting the test from whether the marker works to which pla…
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TL;DR: A 2026 study in Nature Communications found that self-administered finger-prick blood tests for phosphorylated tau 217 (p-tau217), an Alzheimer’s tau marker, and glial fibrillary acidic protein (GFAP), an astrocyte-injury marker, correlated with cogniti…
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TL;DR: A 2026 study in Translational Neurodegeneration found that reducing NDST3, a microtubule deacetylase that affects lysosome acidity, restored lysosomal acidification and reduced amyloid-beta and tau pathology in Alzheimer’s cell and mouse models. Key Fin…
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TL;DR: A 2026 article-in-press study in Alzheimer’s Research & Therapy found that olfactory-region MRI radiomics, a method that turns brain scans into quantitative texture and shape features, linked blood pTau217, a tau-related Alzheimer’s disease biomarker, w…
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TL;DR: A 2026 machine-learning study found that the final SNP-NF model in PLOS One reported mAUC 0.965, recall 0.929, and precision 0.929, while the study reported gains of about 3% in mAUC, 1% in precision, and 0.7% in recall versus their previous neural-proc…
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TL;DR: A 2025 study in Neurochemistry International from Kindai University showed that oral arginine, a naturally occurring amino acid, blocked the formation of toxic amyloid-beta aggregates in lab tests and reduced amyloid pathology in two well-established mo…
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