Research provides new evidence that generalized anxiety disorder (GAD) and depressive disorder (DD) have distinct patterns of brain activity. Machine learning analysis of EEG data reveals signature brain features that may enable more accurate diagnosis. Key Facts: DD showed increased beta band power and complexity compared to GAD Brain network connectivity was altered in both …
New research suggests we may one day be able to vaccinate against depression, reducing suffering. Key facts: Depression is linked to inflammation in the body and brain. Anti-inflammatory treatments improve depression. Environmental factors like lack of contact with “old friends” (microbes we coevolved with) are increasing inflammation and depression. Probiotics, helminths and vaccines that restore …
Depression and cognitive deficits are common health issues that impact millions of people. Scientists are testing a new drug, NSI-189, to see if it can help treat depression and improve thinking ability. Early research shows promise that NSI-189 may be able to grow new brain cells and connections, which could potentially treat depression and boost …
Depression is one of the most common and burdensome mental health disorders globally, affecting over 300 million people. While antidepressant medications can help many patients recover, up to a third do not respond adequately to first-line treatments. This has led doctors to try combining medications in the hopes of better outcomes. One such combination that …
Finasteride is a common medication used to treat hair loss and enlargement of the prostate gland. However, new research shows this drug may also increase the risk of depression and suicidal thoughts. Key Facts: Finasteride works by reducing levels of a hormone called DHT in the body. DHT contributes to hair loss and prostate enlargement. …
A new study shows that delivering brain stimulation with mild electric current to the forehead at home could be an effective treatment option for people with depression. Key facts: The study tested at-home transcranial direct current stimulation (tDCS) in 16 people with moderate to severe depression. Participants had 28 sessions of tDCS over 6 weeks, …
Researchers have discovered that changes in a region deep in the brain called the brainstem may contribute to recurring major depressive disorder (MDD). Key findings include: Patients with first-episode and recurrent depression showed volume decreases in brainstem regions like the pons and midbrain compared to healthy individuals. A region called the superior cerebellar peduncle (SCP) …
Depression affects over 270 million people worldwide. New research is investigating whether manipulating gut bacteria with probiotics, prebiotics or synbiotics can help treat depression symptoms. Key Facts: Probiotics are live microorganisms that provide health benefits when consumed. Prebiotics are food for probiotics. Synbiotics contain both probiotics and prebiotics. A meta-analysis combined results from 13 studies …
Theobromine, an ingredient found in chocolate, may impact mood and depression risk. But the details are complicated. Here’s what the science says so far. Key Facts: A recent study found higher theobromine intake was associated with increased depression risk. However, some experts argue the study had limitations in how it measured depression and theobromine intake. …
Research shows that getting the right amount of the vitamin niacin may help lower the risk of depression. Niacin is one of the B vitamins and is also known as vitamin B3. Consuming too little or too much niacin appears tied to higher odds of depression, suggesting an optimal niacin intake level for depression prevention. …
