Ayahuasca is a traditional psychedelic brew from the Amazon that has been used for centuries in shamanic healing rituals. Research is now exploring its potential therapeutic benefits for mental health and addiction. Key Facts: Ayahuasca contains DMT, a hallucinogenic compound, along with MAOIs from the vine Banisteriopsis caapi. The MAOIs allow the DMT to be …
Borderline personality disorder (BPD) is a complex mental health condition characterized by difficulties with emotional regulation, impulsivity, and unstable relationships. A key feature of BPD is impaired empathy, which contributes to the interpersonal dysfunction seen in these patients. A new review analyzes 45 studies on empathy and related constructs like theory of mind in BPD, …
Social anxiety disorder (SAD), one of the most common anxiety disorders, is characterized by an intense fear of social situations. A new brain imaging study provides evidence that SAD is associated with an overactive serotonin system. Key Takeaways: Using PET imaging, researchers found increased serotonin synthesis and reuptake in multiple brain regions in patients with …
Depression affects over 120 million people worldwide, carrying a heavy burden of disability, mortality, and cost. While medications like SSRIs have provided relief for many, most patients fail to achieve full remission. After 30 years with few advances in pharmaceutical options, it may be time to rethink our approach to treating depression. Exciting new research …
Obsessive-compulsive disorder (OCD) is a complex neuropsychiatric illness impacting approximately 2% of the global population. The disorder is characterized by intrusive, irrational thoughts (obsessions) and repetitive behaviors (compulsions) that patients feel driven to perform. OCD typically follows a chronic course and is associated with significant impairment and reduced quality of life. While effective therapies like …
Brain serotonin is crucially involved in regulating mood, social behavior, and physical health. While medications that alter serotonin levels have revolutionized psychiatry, non-drug approaches may provide safer, sustainable ways to optimize serotonin and promote wellbeing. Key Facts: Brain serotonin influences mood, sociability, and health in animals and humans. Higher serotonin is linked to positive mood, …
Cold stimulus headache, commonly known as “brain freeze”, is a curious and understudied phenomenon that many of us have experienced when eating or drinking something cold too quickly. Though brief and benign, these headaches provide insight into how the brain responds to sudden temperature changes. Key Facts About “Brain Freeze”: Caused by quick exposure of …
A systematic review and meta-analysis published in Scientific Reports evaluated the potential association between chronic fluoride exposure and neurological damage. The study aimed to analyze the impact of fluoride from different sources on neurological disorders in humans. After a thorough literature search, the authors included 27 observational studies in the qualitative analysis. The results showed …
Researchers have uncovered new evidence that a traditional Chinese herbal medicine may be a safe, effective option for treating depression. The formula, known as Chaihu-jia-Longgu-Muli-tang (CLM) also phrased “Chai Hu Jia Long Gu Mu Li Tang,” outperformed standard antidepressants in clinical trials and appears to work via multiple mechanisms in the brain. Key findings: In …
Suicide is a major global public health problem, accounting for over 800,000 deaths worldwide each year. Lithium, a mood stabilizing medication, has been proposed as a novel population-level suicide prevention strategy through supplementation of trace doses into the public drinking water supply. This controversial idea has sparked much debate around its ethics, risks, benefits and …
