Adrenaline Addiction in Rock Climbers: Thrill Seeking Behavior

Extreme sports like rock climbing are often described as “addictive” – but is this just a figure of speech or is there scientific evidence that these sports can produce addiction-like behaviors? A new study took a deep dive into this question, examining withdrawal symptoms in rock climbers during periods of abstinence from climbing. Key Facts: …

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Clonidine for Insomnia & Sleep in Chronic Pain Patients: More Effective Than Zopiclone

A new study published in the Journal of Clinical Sleep Medicine has found that the medication clonidine is more effective and safer than zopiclone for treating insomnia in people with chronic pain. Key findings: Clonidine provided better pain relief than zopiclone. Clonidine helped patients fall asleep faster. Patients felt more rested after taking clonidine compared …

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Modafinil & Serotonin Receptors Influence Gambling Behaviors Like “Loss Chasing”

Gambling is a complex behavior influenced by multiple factors in the brain. New research in mice provides insight into the neurobiology underlying key aspects of gambling such as making the initial decision to gamble and persistently chasing losses. Key Facts: Mice exhibit typical gambling behaviors like choosing to gamble more when odds of winning are …

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Probiotics & Antioxidants: L. Rhamnosus & NAC Reduces Binge Drinking Alcohol

Researchers have identified a powerful combination of drugs that may help treat alcoholism by reducing cravings and blocking relapse. The dual treatment virtually wiped out binge drinking and heavy drinking in an animal model of alcohol addiction. Key Facts: Rats treated with both a probiotic and antioxidants showed a dramatic 90% decrease in relapse-like binge …

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MDMA Assisted Therapy for Alcohol Abuse & PTSD

A new study provides preliminary evidence that MDMA-assisted therapy may help reduce alcohol use in people with severe PTSD. Key facts: MDMA-assisted therapy was tested in a phase 3 clinical trial for treating severe PTSD. Participants were allowed to have mild alcohol or cannabis use disorder. Compared to placebo therapy, MDMA therapy led to greater …

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Soil Bacteria Mycobacterium Vaccae Reduces Anxiety, Stress, Inflammation

Researchers have discovered that a common soil bacterium called Mycobacterium vaccae (M. vaccae) may help reduce stress, anxiety, and inflammation in the brain. Key Facts: M. vaccae is a naturally occurring bacterium found in soil, mud, and water. It is considered harmless to humans. When heat-killed M. vaccae is injected into rats, it reduces stress-induced …

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Vaccine for Depression: Targeting the Immune System & Inflammation

New research suggests we may one day be able to vaccinate against depression, reducing suffering. Key facts: Depression is linked to inflammation in the body and brain. Anti-inflammatory treatments improve depression. Environmental factors like lack of contact with “old friends” (microbes we coevolved with) are increasing inflammation and depression. Probiotics, helminths and vaccines that restore …

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NSI-189 for Depression & Cognitive Enhancement via Neurogenesis & BDNF

Depression and cognitive deficits are common health issues that impact millions of people. Scientists are testing a new drug, NSI-189, to see if it can help treat depression and improve thinking ability. Early research shows promise that NSI-189 may be able to grow new brain cells and connections, which could potentially treat depression and boost …

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California Rocket Fuel for Depression: Mirtazapine & Venlafaxine Combination

Depression is one of the most common and burdensome mental health disorders globally, affecting over 300 million people. While antidepressant medications can help many patients recover, up to a third do not respond adequately to first-line treatments. This has led doctors to try combining medications in the hopes of better outcomes. One such combination that …

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Moon Rock Weed Causes Seizures & Psychosis: Dangers of Potent Marijuana & THC Products

A potent new form of marijuana (cannabis) called “moon rock” has been connected to a troubling case of psychosis and recurring seizures in a young man with no prior history of mental illness or seizures. This case highlights the potential risks of high-potency cannabis products. Key Facts: A 20-year old man with no prior psychiatric …

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