Epilepsy impacts millions of people worldwide. While medications have been the mainstay of treatment, one-third of patients continue to have seizures despite available drugs. This highlights the need for innovative therapies. Recent years have seen exciting developments that bring new promise for improved seizure control. Key Facts: Epilepsy is a neurological disorder characterized by recurrent, …
Research provides new evidence that generalized anxiety disorder (GAD) and depressive disorder (DD) have distinct patterns of brain activity. Machine learning analysis of EEG data reveals signature brain features that may enable more accurate diagnosis. Key Facts: DD showed increased beta band power and complexity compared to GAD Brain network connectivity was altered in both …
Deep brain stimulation (DBS) of a brain region called the ventral capsule/ventral striatum (VC/VS) may provide long-term relief for people with severe, treatment-resistant obsessive-compulsive disorder (OCD), according to a new retrospective study. Key findings: 6 out of 9 people with severe OCD achieved remission after DBS surgery It took an average of 14 months for …
Extreme sports like rock climbing are often described as “addictive” – but is this just a figure of speech or is there scientific evidence that these sports can produce addiction-like behaviors? A new study took a deep dive into this question, examining withdrawal symptoms in rock climbers during periods of abstinence from climbing. Key Facts: …
A new study published in the Journal of Clinical Sleep Medicine has found that the medication clonidine is more effective and safer than zopiclone for treating insomnia in people with chronic pain. Key findings: Clonidine provided better pain relief than zopiclone. Clonidine helped patients fall asleep faster. Patients felt more rested after taking clonidine compared …
Gambling is a complex behavior influenced by multiple factors in the brain. New research in mice provides insight into the neurobiology underlying key aspects of gambling such as making the initial decision to gamble and persistently chasing losses. Key Facts: Mice exhibit typical gambling behaviors like choosing to gamble more when odds of winning are …
Researchers have identified a powerful combination of drugs that may help treat alcoholism by reducing cravings and blocking relapse. The dual treatment virtually wiped out binge drinking and heavy drinking in an animal model of alcohol addiction. Key Facts: Rats treated with both a probiotic and antioxidants showed a dramatic 90% decrease in relapse-like binge …
A new study provides preliminary evidence that MDMA-assisted therapy may help reduce alcohol use in people with severe PTSD. Key facts: MDMA-assisted therapy was tested in a phase 3 clinical trial for treating severe PTSD. Participants were allowed to have mild alcohol or cannabis use disorder. Compared to placebo therapy, MDMA therapy led to greater …
Researchers have discovered that a common soil bacterium called Mycobacterium vaccae (M. vaccae) may help reduce stress, anxiety, and inflammation in the brain. Key Facts: M. vaccae is a naturally occurring bacterium found in soil, mud, and water. It is considered harmless to humans. When heat-killed M. vaccae is injected into rats, it reduces stress-induced …
New research suggests we may one day be able to vaccinate against depression, reducing suffering. Key facts: Depression is linked to inflammation in the body and brain. Anti-inflammatory treatments improve depression. Environmental factors like lack of contact with “old friends” (microbes we coevolved with) are increasing inflammation and depression. Probiotics, helminths and vaccines that restore …
