Infant Music EEG Responses Increased by 3 Months, Movement at 12 Months

Infant Music EEG Responses Increased by 3 Months, Movement at 12 Months

TL;DR: A 2026 study in eLife found that infants’ brains responded more strongly to structured children’s music than shuffled music by 3 months, while clearer music-linked movement patterns appeared mainly by 12 months. Key Findings 79 infants tested: Researchers recorded electroencephalography (EEG), a scalp measure of brain electrical activity, and video-based body movement in 3 …

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Desvenlafaxine Reduced HAM-D17 Scores in Major Depressive Disorder Review

Desvenlafaxine Reduced HAM-D17 Scores in Major Depressive Disorder Review

TL;DR: A 2026 narrative review in Clinical Drug Investigation argued that desvenlafaxine, a serotonin-noradrenaline reuptake inhibitor (SNRI), may be a first-line major depressive disorder option for selected patients, especially when fatigue, cognitive complaints, polypharmacy, or tolerability concerns shape the treatment choice. Key Findings Review plus consensus: The source combined a PubMed-based narrative review with a …

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Celiac Disease Presented With Chronic Insomnia in Single Case Report

Celiac Disease Presented With Chronic Insomnia in Single Case Report

TL;DR: A 2026 case study in International Medical Case Reports Journal described a 42-year-old man whose chronic insomnia improved after celiac disease was diagnosed and treated with a gluten-free diet, but the report cannot prove gluten exposure caused the sleep problem. Key Findings 5 months of insomnia: The patient reported persistent difficulty initiating and maintaining …

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Bipolar Medication Nonadherence Linked to Substance Use and Low Insight

Bipolar Medication Nonadherence Linked to Substance Use and Low Insight

TL;DR: A 2026 systematic review and meta-analysis in Bipolar Disorders found that poor medication adherence in bipolar disorder was linked to substance use, psychotic features, lower insight, poorer functioning, and several markers of more severe illness, but most evidence was graded low or very low quality. Key Findings 19 studies included: Researchers pooled observational studies …

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High-Conflict Divorce Linked to Higher Healthcare Use Over 10 Years

High-Conflict Divorce Linked to Higher Healthcare Use Over 10 Years

TL;DR: A 2026 Danish register study in British Journal of Health Psychology found that higher divorce conflict was linked to more prescriptions, more primary care visits, and higher hospitalisation odds across the years around legal divorce. Key Findings 1,784 Danish divorcees: Researchers linked divorce-conflict survey data to national registers covering medicine prescriptions, primary care visits, …

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Celecoxib Add-On to Antidepressants Reduced Depression Scores: Evidence Very Uncertain

Celecoxib Add-On to Antidepressants Reduced Depression Scores: Evidence Very Uncertain

TL;DR: A 2026 systematic review and meta-analysis in Brain, Behavior, & Immunity – Health found that adding celecoxib to antidepressants was linked to lower depressive symptom scores in 7 small trials, but the efficacy evidence was rated very low certainty. Key Findings 7 randomized trials: The meta-analysis included 365 adults with major depressive disorder, with …

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Neuropsychiatric Genetic Risk Mapped Fluid and Crystallized Cognition

Neuropsychiatric Genetic Risk Mapped Fluid and Crystallized Cognition

TL;DR: A 2026 study in Nature Communications found that neuropsychiatric disorder risk did not map onto cognition as one general trait. Schizophrenia, bipolar disorder, ADHD, autism, and Alzheimer’s disease showed different genetic links with reaction time, fluid reasoning, crystallized knowledge, and noncognitive educational skills. Key Findings 439,000-person GWAS scale: The crystallized-knowledge genome-wide association study had …

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Very Low Nicotine Cigarettes Increased Alternative Nicotine Use

Very Low Nicotine Cigarettes Increased Alternative Nicotine Use

TL;DR: A 2026 secondary analysis in Addiction found that adults switched to very-low-nicotine cigarettes often used alternative nicotine products and maintained much higher nicotine intake than cigarette-only users. Key Findings 438 smokers: The parent randomized clinical trial enrolled adults who smoked 5 to 40 cigarettes per day. 0.4 mg/g cigarettes: The very-low-nicotine-content group received Spectrum …

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Systematic Review Identified Limited Medication Signals for Online Addictions

Systematic Review Identified Limited Medication Signals for Online Addictions

TL;DR: A 2026 systematic review in Future Science OA found early medication evidence for online behavioral addictions, but the 20 included studies were mostly small, male-heavy, and short-term. Key Findings Medication evidence stayed early: The review found small, mixed pharmacotherapy signals across 20 online behavioral addiction studies. Clinical groups stayed small: The 1,016 total participants …

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Depression Nanomedicine Needs More Than Blood-Brain Barrier Delivery

Depression Nanomedicine Needs More Than Blood-Brain Barrier Delivery

TL;DR: A 2026 review in International Journal of Nanomedicine argued that depression nanomedicine should move beyond blood-brain-barrier delivery alone and be judged by target engagement, neuroimmune-barrier-plasticity effects, safety, manufacturability, and patient stratification. Key Findings Mechanism-centered review: The paper organized depression nanomedicine around neuroinflammation, blood-brain-barrier dysfunction, oxidative stress, and impaired neuroplasticity. 3 strategy groups: The review …

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