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TL;DR: A 2026 preprint on medRxiv found that adding 24 IU intranasal oxytocin before 4 mindfulness-based group therapy sessions was linked to larger clinician-rated negative-symptom improvements in a small schizophrenia spectrum disorder pilot trial. Key Findi…
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TL;DR: A 2026 study in The British Journal of Psychiatry found that 4 weeks of twice-weekly subcutaneous racemic ketamine helped a minority of people with treatment-resistant depression, but response fell from 30% at treatment end to 17% 4 weeks later. Key Fin…
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TL;DR: A 2026 trial in Journal of Psychopharmacology found that repeated supervised psilocybin sessions reduced Yale-Brown Obsessive Compulsive Scale (YBOCS) scores, a standard measure of obsession and compulsion severity, in 15 adults with OCD. Key Findings 7…
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TL;DR: A 2026 study protocol in Trials describes COSTS, a randomized trial that will compare cognitive behavioral therapy for insomnia (CBT-I) with standard cognitive behavioral therapy (CBT) in 60 people with treatment-resistant schizophrenia and persistent s…
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TL;DR: A 2026 post-hoc analysis in International Clinical Psychopharmacology found that lurasidone 40 mg/day improved all 5 Positive and Negative Syndrome Scale (PANSS) symptom domains in acute schizophrenia over 6 weeks, with the largest effect on positive sy…
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An innovative study aims to assess the feasibility of patients self-managing transcranial direct current stimulation (tDCS) therapy for depression at home. This digitally-supported model could greatly expand access if proven safe, reliable and effective. Key F…
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A new randomized, double-blind, placebo-controlled clinical trial provides evidence that a green coffee bean extract standardized to chlorogenic acids (CGA-7) can help with weight loss in healthy overweight adults. Key facts: CGA-7 supplementation for 12 weeks…
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A new study published in the journal Mædica – a Journal of Clinical Medicine compared the antidepressant effects of modafinil versus citalopram for treating major depressive disorder (MDD). The medications were equally effective at reducing depressive symptoms…
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