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TL;DR: A Swedish study of 42 people with depression found no link between the brain’s main calming chemical, GABA, and slowed movement, early waking or poor appetite. The researchers measured GABA with two kinds of scans, but most patients had fairly mild vers…
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TL;DR: A 2026 rat study in Brain Structure and Function found that ventral pallidum activity supports juvenile social play, while activating inhibitory nucleus accumbens inputs to the ventral pallidum reduced play behavior in both male and female rats. Key Fin…
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TL;DR: A 2026 preprint in medRxiv linked recurrent major depression to direction-specific effective-connectivity changes, with strongest patterns in cerebellar-cortical, sensorimotor, cognitive, neurotransmitter, and oligodendrocyte precursor cell maps. Key Fi…
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TL;DR: A 2026 study in Journal of Exposure Science & Environmental Epidemiology linked prenatal PM2.5 and non-freeway NOx exposure with newborn amino-acid metabolism pathways that also tracked autism spectrum disorder (ASD) diagnosis before age 5. Key Findings…
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TL;DR: A 2026 Human Brain Mapping study combined PET receptor imaging with speech functional MRI, or fMRI, in healthy adults and found that GABA signaling and striatal dopamine release interacted with brain activity during human speech control. Key Findings PE…
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TL;DR: A 2026 human microbiome and intervention study in Nature Communications found that coffee drinkers showed distinct gut microbiome composition and lower several microbial metabolites, while caffeinated and decaffeinated coffee shifted stress and mood mea…
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Food provides the building blocks for our mental and physical health. New research reveals that many common foods supply key neurotransmitters that regulate brain and nervous system function. Understanding how our diet provides these crucial molecules opens up…
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A new pilot study investigates using kava and valerian, two herbal remedies, to treat stress-induced insomnia. Key Facts: 24 patients with stress-induced insomnia took part in the 6-month crossover study. All patients took kava for 6 weeks, then valerian for 6…
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Phenibut is an experimental drug that was discovered in Russia in the 1960s and has shown promise as a treatment for anxiety, improving brain function, and enhancing quality of life. Key facts about phenibut: It is derived from gamma-aminobutyric acid (GABA),…
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Phenibut is a substance that acts on the brain and can cause dependence and addiction. Stopping phenibut suddenly after regular use leads to a withdrawal syndrome with potentially serious health consequences. What is Phenibut? Phenibut is a central nervous sys…
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