Psychosis in Lupus Linked to Immune Disease Activity in Review

Psychosis in Lupus Linked to Immune Disease Activity in Review

TL;DR: A 2026 systematic review and meta-analysis in Lupus found that psychosis affected about 4.5% of adults with systemic lupus erythematosus (SLE), was more common in neuropsychiatric SLE, and tracked most strongly with active immune disease markers rather than serving as a stand-alone psychiatric label. Key Findings Sixty-five studies were included: The review covered 31,495 …

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Head Impact MEG Changes Mapped to Neurochemical Brain Systems

Head Impact MEG Changes Mapped to Neurochemical Brain Systems

TL;DR: A 2026 preprint in medRxiv found that head-impact-related magnetoencephalography (MEG) changes in high-school football players were strongest in cortical regions matching specific neurotransmitter and gene-expression maps, especially norepinephrine, nicotinic acetylcholine, APOE, and BDNF-related patterns. Key Findings MEG tracked pre-to-post-season brain signaling across 278 timepoints from 91 male high-school football players. Concussion-related cortical slowing aligned …

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fMRI Noise Signal Tracked Nicotine Craving and Stimulant Effects

fMRI Noise Signal Tracked Nicotine Craving and Stimulant Effects

TL;DR: A 2026 study in Biological Psychiatry: Global Open Science found that systemic low-frequency oscillation (sLFO), a slow whole-body physiology readout usually treated as functional MRI noise, tracked nicotine dependence, cue-induced craving, abstinence, and stimulant-related task performance across four fMRI cohorts. Key Findings The study analyzed four fMRI cohorts: Researchers examined a 64-person cigarette cue-reactivity …

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Early Psychosis Linked to Work and Education Disruption in SEEearly Cohort

Early Psychosis Linked to Work and Education Disruption in SEEearly Cohort

TL;DR: A 2026 study in European Archives of Psychiatry and Clinical Neuroscience found that more than half of 184 young adults entering an early-psychosis supported employment and education trial were not in work, school, or training, even though nearly all had finished at least lower- or upper-secondary schooling. Key Findings The SEEearly cohort included 184 …

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Blood miRNAs Linked to Hippocampal Volume and Brain Atrophy

Blood miRNAs Linked to Hippocampal Volume and Brain Atrophy

TL;DR: A 2026 Molecular Psychiatry study linked blood-derived microRNAs, short RNA regulators that help control gene expression, to left hippocampal volume and later brain atrophy in adults from the Rhineland Study. Key Findings Baseline MRI cohort: Researchers compared blood microRNA expression in 2,062 adults with baseline MRI measures of left and right hippocampal volume, hippocampal …

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Youth Cannabis Use Linked to Flatter Cognitive Development

Youth Cannabis Use Linked to Flatter Cognitive Development

TL;DR: A 2026 Neuropsychopharmacology study of 11,036 ABCD participants found youth who initiated cannabis use showed flatter cognitive-development trajectories from ages 9 to 17, with hair-detected THC linked to worse episodic-memory change. Key Findings 11,036 youth were followed: Researchers used the Adolescent Brain Cognitive Development (ABCD) Study to track neurocognitive performance from late childhood into …

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Young Men Reported More Dominance-Seeking Moral Grandstanding

Young Men Reported More Dominance-Seeking Moral Grandstanding

TL;DR: A 2026 study in Political Psychology found that men ages 18 to 35 reported the highest levels of dominance-seeking moral grandstanding, a form of moral expression aimed at putting opponents down rather than only defending a belief. Key Findings Dominance-seeking moral grandstanding was highest among men ages 18 to 35. Four-country survey: 8,420 adults …

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When Biopolymer Injections End in Delusional Infestation

When Biopolymer Injections End in Delusional Infestation

TL;DR: A 2026 study in Cureus found that a 55-year-old woman developed anxiety, somatic hypervigilance, and eventual delusional infestation after illicit cosmetic biopolymer injections, raising the possibility that chronic inflammatory exposure can help tip vulnerable patients into a secondary Ekbom syndrome. Key Findings One 55-year-old patient with no prior psychiatric history: The case centers on …

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Visual Distraction Strengthened the Oblique Effect in Working Memory

Visual Distraction Strengthened the Oblique Effect in Working Memory

TL;DR: A 2026 study in Cognitive, Affective, & Behavioral Neuroscience found that visual working memory, the short-term holding of visual details, still showed a strong cardinal-versus-diagonal orientation bias under distraction, while transcranial direct current stimulation (tDCS), a weak noninvasive brain-stimulation method, did not improve task reports. Key Findings Two stimulation experiments tested orientation memory: Researchers …

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Violent Pornography Arousal Linked to Learning, Not Evolution

Violent Pornography Arousal Linked to Learning, Not Evolution

TL;DR: A 2026 study in Journal of Sex Research found that in 571 German women, arousal to an aggressive written sexual narrative was better explained by sex drive, rape myth acceptance, and prior violent pornography exposure than by evolutionary life-history markers. Key Findings 571 women were quota-sampled: The German sample was selected to reflect age …

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