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TL;DR: In a crossover trial of 119 adults living near busy highways, a month with a real HEPA air purifier did not clearly speed up a thinking test across the whole group. Among adults 40 and older, though, participants finished the harder test 12% faster afte…
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TL;DR: A 2026 mouse study in Nature found that age-related gut microbiome changes impaired vagal gut-brain signaling and hippocampal memory encoding, while several interventions restored memory performance in aged or microbiome-aged mice. Key Findings Aged mic…
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TL;DR: A 2026 cohort study in PLOS One found that higher fasting plasma vitamin C levels were independently associated with larger MRI-measured gray matter and stronger default mode network (DMN) structural connectivity in 2,044 older adults, but the cross-sec…
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TL;DR: A 2026 study in Epigenetics found that DNA methylation clocks, which estimate biological aging from chemical marks on DNA, gave substantially older age estimates in saliva than in two blood-derived samples from 91 early-to-mid-adult participants. Key Fi…
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TL;DR: A 2026 medRxiv preprint found that older adults with Montreal Cognitive Assessment (MoCA)-defined mild cognitive impairment had less coordinated pulse-wave responses during a cognitive challenge than cognitively intact older adults. Key Findings Communi…
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TL;DR: A 2026 medRxiv preprint found that specific AD8 dementia-screening items, especially judgment, repetition, finances, tool use, and daily memory problems, tracked functional and psychosocial vulnerability in 144 Chinese-speaking older adults. Key Finding…
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TL;DR: A 2025 study in The Journal of Prevention of Alzheimer’s Disease found that stress internalization, not acculturation or activity engagement, predicted memory decline across three waves in 1,528 older Chinese Americans. Key Findings Stress internalizati…
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Loneliness Lowered Memory Without Speeding Decline TL;DR: In 10,217 older Europeans, loneliness was linked to lower immediate and delayed recall at baseline, but it did not make memory decline faster over 6 years. Key Findings 10,217 SHARE participants: The an…
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