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TL;DR: A 2026 study in Neuropsychopharmacology found that 30 mg 2C-B produced acute subjective effects in healthy adults that were similar in overall intensity to 125 mg MDMA, shorter and less distressing than 25 mg psilocybin, and less cardiovascularly stimul…
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TL;DR: A 2026 Neuropsychopharmacology study of 11,036 ABCD participants found youth who initiated cannabis use showed flatter cognitive-development trajectories from ages 9 to 17, with hair-detected THC linked to worse episodic-memory change. Key Findings 11,0…
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TL;DR: A 2026 paper in Neuropsychopharmacology argued that cannabidiol (CBD), a non-intoxicating cannabis compound, has plausible psychiatric and neurological uses, but clinical claims need standardized products, exposure tracking, and safety monitoring before…
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TL;DR: A 2026 rat study in Neuropsychopharmacology reported that repeated semaglutide treatment reduced cocaine-vs-food choice in male and female rats, supporting further clinical testing for cocaine use disorder rather than proving human benefit. Key Findings…
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TL;DR: A 2026 study in Neuropsychopharmacology found that decision-making measures from a stop-signal task, especially evidence accumulation, predicted cigarette and cannabis use better than stop-signal reaction time (SSRT), a common estimate of response inhib…
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TL;DR: A 2026 rat study in Neuropsychopharmacology found that PACAP/PAC1 signaling in the lateral septum changed forced-swim coping, ACTH stress-hormone release, open-arm exploration, and grooming behavior. Key Findings Stress changed PACAP signals by brain re…
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TL;DR: A 2026 PTSD neuroimaging and language-analysis study in Neuropsychopharmacology found that hippocampal activity encoded specific semantic content of traumatic and neutral autobiographical memories, while greater hippocampal sensitivity to autobiographic…
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TL;DR: A 2026 systematic review and meta-analysis in Neuropsychopharmacology found that dopamine D2-like receptor activation suppressed glucose-stimulated insulin secretion (GSIS), insulin release after high glucose, in animal pancreatic cells, suggesting one…
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