EXPLORE THE SCIENCE
TL;DR: A meta-analysis pooling 63 studies and 265,079 people found that cannabis users had about twice the odds of committing violence as non-users (2.05 times in the general population, 2.49 times among psychiatric patients). The gap shrank to 1.17 times in s…
Read article
TL;DR: A 2026 systematic review and meta-analysis in Lupus found that psychosis affected about 4.5% of adults with systemic lupus erythematosus (SLE), was more common in neuropsychiatric SLE, and tracked most strongly with active immune disease markers rather…
Read article
TL;DR: A 2026 study protocol in Trials describes COSTS, a randomized trial that will compare cognitive behavioral therapy for insomnia (CBT-I) with standard cognitive behavioral therapy (CBT) in 60 people with treatment-resistant schizophrenia and persistent s…
Read article
TL;DR: A 2026 case study in Psychiatry and Clinical Neurosciences Reports described a 36-year-old man with treatment-resistant schizophrenia and focal epilepsy whose psychosis improved after slow clozapine titration, without worsening seizure frequency or seve…
Read article
TL;DR: A 2026 preprint in medRxiv used 18F-DOPA positron emission tomography (PET) to estimate dopamine synthesis and storage, and found that caudate dopamine synthesis decreased as schizophrenia patients moved from active psychosis into early psychotic remiss…
Read article
TL;DR: A 2026 randomized study in Psychological Medicine found that right orbitofrontal cortex repetitive transcranial magnetic stimulation (rTMS), a noninvasive brain-stimulation method, improved visuospatial memory on the Brief Visuospatial Memory Test-Revis…
Read article
TL;DR: A 2026 study in The British Journal of Psychiatry found that in first-episode psychosis, MRI deviations from age-matched brain norms at illness onset helped predict which patients would carry heavier symptom burdens and poorer functioning for years afte…
Read article
TL;DR: A 2026 study in The British Journal of Psychiatry found that serious mental illness labels shifted often in real-world psychiatric records: 64% of patients with schizophrenia, bipolar disorder, or severe major depression received multiple diagnoses over…
Read article
TL;DR: A 2026 systematic review in The British Journal of Psychiatry linked schizophrenia to a multisystem advanced-aging phenotype, including older-appearing brain scans, shorter telomeres, inflammation, and higher dementia risk. Key Findings 170 studies incl…
Read article
Childhood Loneliness Multiplied Psychosis Risk in EU-GEI TL;DR: Loneliness that started before age 12 and persisted into adolescence tracked with sharply higher schizophrenia-spectrum risk, especially when it stacked on top of genetic liability. Key Findings P…
Read article