Brainstem Expiratory Neurons Drove Neurogenic Hypertension

Brainstem Expiratory Neurons Drove Hypertension

Brainstem Expiratory Neurons Drove Hypertension TL;DR: A brainstem region involved in forceful exhalation also appears to drive blood-vessel constriction, making it a possible target for some forms of neurogenic hypertension. Key Findings A forced-exhalation region joined the pressure mechanism: The lateral parafacial region, normally recruited for strong expiration, was active under hypertensive conditions. Blood-vessel nerves …

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Early Life Stress Rewired Gut Nerves and Visceral Pain Pathways

Early Stress Rewired the Gut's Nerves, Not Just the Brain

Early Stress Rewired the Gut’s Nerves, Not Just the Brain TL;DR: Early life stress produced lasting gut pain and motility changes through enteric and sympathetic nerve pathways, with pediatric cohort data pointing in the same direction. Key Findings Maternal separation produced gut hypersensitivity: The mouse model developed visceral pain sensitivity and lasting motility defects. Motility …

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The Silent Killer: How Loneliness Weakens Monkeys’ Immunity & What It Means for Humans

Feeling lonely and socially isolated is associated with poorer health outcomes and increased risk of early mortality. Research in monkeys now reveals how loneliness impacts the immune system, providing clues into the mechanisms underlying the health risks of loneliness. Key Facts: Lonely monkeys show altered activity in the sympathetic nervous system and compromised immune cell …

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