Biological Roots of Criminal Behaviors: Physiology, Brain Structure & Function, Genetics

Criminal behavior has complex origins. While social and psychological factors play a clear role, a growing body of research suggests biological factors also influence criminality. Here’s what the science says so far about the biology underlying criminal behavior. Key Facts: Genetics account for 40-60% of variance in antisocial behavior. Environmental factors also play a role. …

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Semaglutide: The Popular GLP-1 Receptor Agonist with Many Potential Medical Uses

Semaglutide is emerging as a wonder drug for management of various metabolic diseases. Originally approved for type 2 diabetes, this glucagon like peptide-1 (GLP-1) receptor agonist is now showing promise for treating obesity, non-alcoholic steatohepatitis (NASH), and neurodegenerative diseases like Alzheimer’s and Parkinson’s. Let’s explore the therapeutic potential of semaglutide and how it acts as …

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Pharmacogenomics: Genetics Determine Weight Gain & Loss from Drugs & Medications

Obesity has reached epidemic levels globally, with serious health and economic consequences. While lifestyle factors play a key role, genetics also influence a person’s susceptibility to weight gain or difficulty losing weight. An emerging field called pharmacogenomics is uncovering how genetics impacts response to medications that cause weight gain as a side effect, as well …

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Empathy Differences in Liberals vs. Conservatives: Brain Scans Reveal (Study)

A new study reveals that people who identify as liberal or left-leaning politically exhibit greater neural empathy responses compared to conservatives. The findings provide novel neuroscientific evidence that ideological differences extend to brain function during empathy. Key Facts: Researchers used MEG brain imaging to measure neural empathy responses in 55 participants as they observed others’ …

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Neurobiological Correlates of Human Intelligence (IQ): Genetics, Brain Regions, Cellular Structures

Human intelligence is a complex cognitive trait that has fascinated scientists and philosophers for centuries. New research is shedding light on the neurobiological underpinnings of intelligence, from genes to cells to brain networks. Key Facts: Intelligence is one of the most heritable human behavioral traits, with genetics explaining 50-80% of variability between individuals. Over 1000 …

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Neuroanatomy of Intelligence (IQ): Correlates from MRI Research

Human intelligence has long fascinated scientists. With modern neuroimaging methods like MRI, we now have an unprecedented ability to examine the biological basis of intelligence in the living brain. Key Facts: Larger brain size predicts greater intelligence, but regional brain volumes matter more than total size. More intelligent individuals tend to have greater volumes in …

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MDPV Mechanisms of Action: Neurochemical Effects of the Synthetic Cathinone

Synthetic cathinones like MDPV emerged as drugs of abuse in the early 2010s, gaining notoriety for their powerful stimulant effects and association with bizarre intoxication and death. Despite legislation banning MDPV and its analogs, these substances continue circulating in the drug marketplace. Understanding the pharmacology of MDPV provides insight on its abuse liability, toxic effects, …

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Kava Kava for Anxiety Treatment: Effective Short-Term But Uncertain Long-Term

Kava kava, an herbal supplement made from the root of Piper methysticum, has gained popularity as an alternative treatment for anxiety and insomnia. A recent systematic review and meta-analysis re-examined kava kava’s effectiveness and safety for anxiety disorders. The authors concluded that kava kava is effective for short-term anxiety relief but long-term safety remains uncertain. …

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Low-Dose Amphetamine Restores Dopamine Transporters in Cocaine Addiction, Rat Study

Cocaine abuse leads to dysfunction of brain dopamine systems and the development of addiction. New research identifies changes in the dopamine transporter as a driving force underlying cocaine addiction, and points to a novel way to reverse these detrimental effects. Key Facts: Cocaine abuse caused the dopamine transporter to form larger complexes of multiple transporter …

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