Depression Linked to Lower Quality of Life in Older Adults in Nepal

Depression Linked to Lower Quality of Life in Older Adults in Nepal

TL;DR: A 2026 cross-sectional study in BMC Geriatrics found that 43.9% of 945 older adults in Nepal’s Sudurpaschim Province screened positive for geriatric depression, and depression was linked to lower quality-of-life scores across every WHOQoL-8 domain. Key Findings Large household sample: Researchers interviewed 945 adults aged 60 years and older in Hill and Tarai districts …

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Problematic Sexual Behaviour Linked to NSSI Most Strongly in Women

Problematic Sexual Behaviour Linked to NSSI Most Strongly in Women

TL;DR: A 2026 medRxiv preprint found that problematic sexual behaviour was associated with non-suicidal self-injury in a university cohort, with the strongest pattern in women. Key Findings 2,666 people were analyzed: The study included 2,189 university participants and 477 clinical patients with problematic sexual behaviour. NSSI rates were similar overall: Non-suicidal self-injury was reported by …

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Newborn Metabolomics Linked Prenatal Air Pollution to Autism Risk Pathways

Newborn Metabolomics Linked Prenatal Air Pollution to Autism Risk Pathways

TL;DR: A 2026 study in Journal of Exposure Science & Environmental Epidemiology linked prenatal PM2.5 and non-freeway NOx exposure with newborn amino-acid metabolism pathways that also tracked autism spectrum disorder (ASD) diagnosis before age 5. Key Findings 100 newborn blood spots: Researchers analyzed 50 children later diagnosed with ASD and 50 matched controls from Kaiser …

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Fashion Satisfaction Tracked Better Well-Being in Middle-Aged Women

Fashion Satisfaction Tracked Better Well-Being in Middle-Aged Women

TL;DR: A 2026 study in Journal of Macromarketing found that middle-aged women who were more satisfied with available clothing options reported better mental well-being, partly because they were less likely to avoid social situations over appearance distress. Key Findings Study sample: 252 UK women ages 38 to 67 completed surveys on clothing satisfaction, well-being, aging …

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Machine Learning Predicted Mindfulness App Engagement in Generalized Anxiety Disorder

Machine Learning Predicted Mindfulness App Engagement in Generalized Anxiety Disorder

TL;DR: A 2026 study in Journal of Affective Disorders used interpretable machine learning to predict who completed more prompts during a 14-day mindfulness app trial for generalized anxiety disorder. Key Findings Trial size: A two-arm randomized trial included 110 people with generalized anxiety disorder, assigned to a mindfulness ecological momentary intervention or a self-monitoring app. …

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Maternal COVID Immune Signatures Were Linked to Infant Neurodevelopmental Screening Risk

Maternal COVID Immune Signatures Were Linked to Infant Neurodevelopmental Screening Risk

TL;DR: A 2026 Communications Biology study associated maternal SARS-CoV-2 infection during pregnancy with more positive toddler autism-risk screens and newborn immune-protein patterns tied to nicotinamide metabolism, microglial activation, and neutrophil activity. Key Findings Positive M-CHAT-R/F screens, a toddler autism-risk screening result, occurred in 10.1% of 218 SARS-CoV-2-exposed children versus 5.7% of 527 pre-pandemic controls. Earlier …

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Major Upper-Limb Amputation Linked to Higher Mental Health Diagnoses

Major Upper-Limb Amputation Linked to Higher Mental Health Diagnoses

TL;DR: A 2026 retrospective database study in Archives of Orthopaedic and Trauma Surgery found that people with major upper-extremity amputations had higher one-year rates of new mental-health diagnoses, antidepressant starts, and psychotherapy use than matched patients with minor hand or digit amputations. Key Findings Matched database study: Researchers compared 1,226 major upper-extremity amputation patients with …

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Loneliness Linked Alzheimer’s Disease and Suicide Risk Signals

Loneliness Linked Alzheimer's Disease and Suicide Risk Signals

TL;DR: A 2026 systematic review and meta-analysis in Psychogeriatrics linked loneliness with Alzheimer’s disease and several forms of suicidal behavior, with especially strong shared correlations for hopelessness, insomnia, entrapment, and stress. Key Findings 316 studies reviewed: Researchers found 44 studies on loneliness and Alzheimer’s disease, 261 on loneliness and suicide, and no original study that …

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GLP-1 Receptor Agonists Linked to Small Hypersomnolence Risk Increase

GLP-1 Receptor Agonists Linked to Small Hypersomnolence Risk Increase

TL;DR: A 2026 real-world cohort study in Journal of Diabetes & Metabolic Disorders linked GLP-1 receptor agonists, drugs targeting a glucose-related metabolic hormone pathway, to a higher hazard of new hypersomnolence, but the absolute risk increase was small. Key Findings 237,986 matched patients: The TriNetX analysis compared 118,993 GLP-1 receptor agonist users with 118,993 matched …

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Frontal Midline Theta Linked Negative Emotionality to Weaker Cognitive Control

Frontal Midline Theta Linked Negative Emotionality to Weaker Cognitive Control

TL;DR: A 2026 study in Cognitive, Affective, & Behavioral Neuroscience found that lower frontal midline theta, an EEG marker of cognitive-control engagement, partly explained why young adults with higher negative emotionality performed worse on a Go/No-Go inhibition task. Key Findings 106 young adults completed EEG testing: U.S. Army National Guard recruits performed a Go/No-Go task …

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