Dopamine in Parkinsons Disease: Insights & Future Therapies

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the loss of dopamine-producing neurons. Dopamine plays an important role in PD development. Here are some key facts: Dopamine is a chemical messenger in the brain involved in movement, motivation, and mood. Loss of dopamine-producing neurons causes the motor symptoms of PD like tremors, rigidity, and …

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Link Between Insomnia, Short Sleep Duration, Dementia Risk: Insights from a 19-Year Swedish Study

Trouble sleeping may raise your risk of dementia later in life, according to a new 19-year study of over 22,000 middle-aged and older adults in Sweden. Both insomnia symptoms and shorter sleep were linked to higher chances of developing dementia down the road. Key facts: Adults reporting insomnia symptoms had an 18% higher risk of …

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New Alzheimer’s Drug Aducanumab Promising But “ARIA” Side Effects Require Careful Monitoring

A new drug recently approved for Alzheimer’s disease aims to treat the underlying cause of the condition by removing amyloid plaques in the brain. Though promising, the drug called aducanumab also comes with potential side effects that require careful monitoring. Key facts: Aducanumab is the first drug that targets and removes amyloid plaques, sticky buildups …

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Gut-Brain Connection in Parkinson’s: Immune System’s Role in Early Gastrointestinal Symptoms

A new study in mice shows how the immune system may play a role in the early gastrointestinal symptoms of Parkinson’s disease, decades before movement problems develop. Researchers found that injecting a specific piece of the alpha-synuclein protein into genetically modified mice triggered inflammation and loss of nerve cells in the gut, leading to constipation …

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Iron-Induced Cell Death & Alzheimers: The Microglia Connection

Researchers have uncovered an important new mechanism that causes inflammation and damage to the brain’s white matter in Alzheimer’s disease. This discovery about how brain cells called microglia die could lead to new Alzheimer’s treatments. Key Facts: The study found that microglia, which are immune cells in the brain, die through a process called “ferroptosis” …

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Apolipoprotein E (ApoE) Levels & Alzheimer’s Disease Risk: Findings from a Large Genetics Study

A new large genetics study has discovered new clues into how levels of a protein called apolipoprotein E (ApoE) in the blood may influence a person’s risk of developing Alzheimer’s disease. Key facts: Researchers found 9 new genetic variants that influence ApoE levels in the blood. Some raise levels, while others lower levels. People with …

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