Neuroscience

Antipsychotic Dose Was Not Linked to MoCA Cognitive Scores in Young Adults With Schizophrenia

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Antipsychotic Dose Was Not Linked to MoCA Cognitive Scores in Young Adults With Schizophrenia

TL;DR: A 2026 BMC Psychiatry study found that antipsychotic dose was not associated with Montreal Cognitive Assessment (MoCA), a brief cognitive screening test, in clinically stable schizophrenia patients under 40, while higher symptom scores and longer illness duration tracked lower cognition. Key Findings Forty-one clinically stable outpatients with schizophrenia were included after researchers screened a …

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Anti-GlyR PERM Case Linked Myoclonus to Respiratory Failure

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Anti-GlyR PERM Case Linked Myoclonus to Respiratory Failure

TL;DR: A case study published in 2026 in BMC Neurology described a 45-year-old man with acute anti-glycine receptor progressive encephalomyelitis with rigidity and myoclonus (PERM), a stiff-person-spectrum disorder, whose sound-triggered muscle jerks repeatedly drove oxygen saturation down to 30% before immunotherapy and plasma exchange were followed by recovery. Key Findings Acute onset: Symptoms developed over …

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ADHD Symptoms Were Linked to Extremely Severe Chronic Pain

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ADHD Symptoms Were Linked to Extremely Severe Chronic Pain

TL;DR: A 2026 cross-sectional study in Scientific Reports found that attention-deficit/hyperactivity disorder (ADHD) symptom screening was linked to extremely severe chronic pain in 958 adults at Japanese pain centers, while autism spectrum disorder (ASD) screening was not clearly tied to pain intensity. Key Findings Referral pain sample: Researchers analyzed 958 adults with persistent chronic pain …

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For Baby’s Sake Linked DVA Recognition With Parenting Change

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For Baby's Sake Linked DVA Recognition With Parenting Change

TL;DR: A 2026 qualitative study in BMC Psychology reported that the For Baby’s Sake whole-family domestic violence and abuse programme was linked to parents’ perceived changes in abuse recognition, emotion regulation, and parenting behavior across pregnancy-to-two-year interviews. Key Findings 83 interviews: Researchers analyzed 83 interviews from 39 parents enrolled in the For Baby’s Sake programme. …

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VNS Reduced Seizures After Failed Epilepsy Surgery in CORE-VNS

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VNS Reduced Seizures After Failed Epilepsy Surgery in CORE-VNS

TL;DR: A 2026 preprint in medRxiv from the CORE-VNS study reported that vagus nerve stimulation (VNS), a neuromodulation therapy for drug-resistant epilepsy, produced similar 36-month seizure reductions in people with and without prior intracranial epilepsy surgery. Key Findings 531 VNS implants: The analysis included 531 people with drug-resistant epilepsy who received an initial VNS implant …

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DLPFC tDCS Improved MoCA and Depression Scores in Chemo-Brain Case Report

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DLPFC tDCS Improved MoCA and Depression Scores in Chemo-Brain Case Report

TL;DR: A 2026 study in Journal of Medical Case Reports described a 71-year-old breast-cancer survivor whose Montreal Cognitive Assessment (MoCA), a cognitive screening test, increased from 16 to 20 and whose 15-item Geriatric Depression Scale (GDS-15), a depression-symptom questionnaire, decreased from 8 to 2 after 12 sessions of left DLPFC, a prefrontal executive-control region, transcranial …

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Sympathetic Nerves Slowed Mouse Melanoma via Norepinephrine on Alpha Adrenergic Receptors on Macrophages

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Sympathetic Nerves Slowed Mouse Melanoma via Norepinephrine on Alpha Adrenergic Receptors on Macrophages

TL;DR: A 2026 study in Neuron from Weill Cornell used mouse melanoma models to find that sympathetic nerves growing into tumors release norepinephrine, which activates alpha adrenergic receptors on tumor-associated macrophages and reduces their pro-tumor numbers — flipping the conventional view of the nervous system as a cancer accelerator into evidence that one branch of …

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Sweetness Expectations Changed Midbrain Reward Signals

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Sweetness Expectations Changed Midbrain Reward Signals

TL;DR: A 2026 study in Journal of Neuroscience found that when people expected sugar, an artificially sweetened drink became more pleasant and produced a stronger midbrain response, even though perceived sweetness was similar. Key Findings Expectation changed the reward readout: The researchers selected participants who reported similar perceptual experiences of sugar and non-nutritive sweetener. 27 …

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Subgaleal ISP Stimulation Reduced Treatment-Resistant Epilepsy Seizures

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Subgaleal ISP Stimulation Reduced Treatment-Resistant Epilepsy Seizures

TL;DR: A 2026 medRxiv preprint reported that closed-loop subgaleal intersectional short-pulse stimulation reduced seizure duration and rapidly lowered seizure incidence in a small first-in-human treatment-resistant epilepsy study. Key Findings Subgaleal implantation reached 13 patients: Researchers enrolled 15 adults, 2 withdrew before implantation, and 13 underwent subgaleal electrode implantation and inpatient monitoring. 2,283 hours of video-EEG …

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NLP Stroke Subtyping Linked Lobar ICH to Dementia and Cortical Stroke to MI

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NLP Stroke Subtyping Linked Lobar ICH to Dementia and Cortical Stroke to MI

TL;DR: A 2026 preprint in medRxiv used natural language processing (NLP) on Scottish CT and MRI reports to subtype stroke at scale, linking lobar intracerebral hemorrhage to higher later dementia risk and cortical ischemic stroke to higher early myocardial infarction risk. Key Findings 785,331 head scans: Researchers applied NLP to CT and MRI head-scan reports …

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