Neurostimulation

Future Potential of Low Intensity Focused Ultrasound (LIFU): Non-Invasive Reversible Brain Stimulation

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Low intensity focused ultrasound (LIFU) is an exciting new non-invasive brain stimulation technology that allows precise neuromodulation of deep brain structures without surgery. Early research shows LIFU can safely and reversibly modulate targeted areas of the brain using sound waves, opening doors for understanding and treating psychiatric illnesses. Key Facts: LIFU uses acoustic energy to …

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Focused Ultrasound Stimulation of the Prefrontal Cortex Treats Depression in Mice

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A new study published in Frontiers in Psychiatry provides promising evidence that focused ultrasound stimulation of the prefrontal cortex can alleviate depressive behaviors in mice by suppressing inflammatory responses. Key facts: Researchers stimulated the prefrontal cortex of mice with focused ultrasound for 30 minutes. Mice treated with ultrasound showed less depressive behaviors compared to sham …

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Focused Ultrasound (FUS): An Effective Treatment for Depression in Rat Study

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New research demonstrates that repeated focused ultrasound treatments can have antidepressant-like effects in rats. The non-invasive technique was able to improve performance on a common test of depressive behaviors. While not a silver bullet solution, focused ultrasound represents an exciting potential alternative for depression treatment. Key Facts: Focused ultrasound (FUS) uses targeted sound waves to …

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Transcranial Ultrasound Stimulation: Benefits & Future Applications

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Our brains contain around 100 billion neurons communicating through an intricate web of connections. This complex circuitry controls everything we think, feel, and do. But sometimes things can go wrong, leading to neurological disorders like epilepsy, Parkinson’s disease, depression and Alzheimer’s. An exciting new approach called transcranial ultrasound stimulation (TUS) is showing great promise as …

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Focused Ultrasound (FUS): A Transformative Noninvasive Brain Treatment

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Focused ultrasound (FUS) is an exciting noninvasive brain treatment technology that is revolutionizing how we approach neurological and psychiatric diseases. This incisionless technique uses precisely targeted sound waves to therapeutically stimulate or ablate brain tissue. The Big Picture: FUS uses focused, high-intensity sound waves to precisely treat diseased brain regions without incisions. It has FDA …

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Brain-Computer Interfaces: Advances, Applications, Ethics (2023)

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Invasive brain-computer interfaces (BCIs) allow for direct communication between the brain and external devices, offering immense potential for restoring lost functions and even enhancing brain capabilities. Recent advances are bringing this emerging technology closer to widespread clinical use. Invasive BCIs involve surgically implanted electrodes to record from or stimulate the brain. This allows for much …

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TACS for Schizophrenia: Early Promise of Transcranial Alternating Current Stimulation

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Schizophrenia is a severe mental disorder affecting about 1% of the population worldwide. It is characterized by hallucinations, delusions, disorganized thinking and behavior, and impaired cognitive functioning. Current treatments with antipsychotic medications are helpful but have significant limitations, especially for cognitive deficits and negative symptoms like social withdrawal and lack of motivation. This has driven …

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TDCS for Trichotillomania: Brain Stimulation Shows Promise for Hair Pulling Disorder in 25-Year-Old Female

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A new case study provides initial evidence that transcranial direct current stimulation (tDCS) may be an effective treatment option for trichotillomania, also known as hair pulling disorder. The study tested an intensified, repeated tDCS protocol targeting the supplementary motor area and dorsolateral prefrontal cortex in a 25-year-old woman with trichotillomania. After 16 sessions over 20 …

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Transcranial Brain Stimulation for Insomnia & Sleep: TES & TMS Efficacy

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Insomnia is a highly prevalent sleep disorder affecting up to 35% of the general population – and can significantly impair quality of life. Researchers have been investigating new non-pharmacological treatment options like transcranial electric stimulation (TES) and repetitive transcranial magnetic stimulation (rTMS) to treat insomnia symptoms. A new meta-analysis published in Frontiers in Psychiatry reviewed …

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Neuralink Brain-Machine Interface: High-Bandwidth Connection to Neurons?

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Neuralink, a neurotechnology company founded by Elon Musk, has developed a novel brain-machine interface system with unprecedented electrode density and bandwidth. In a recent white paper, Neuralink scientists describe their progress towards a scalable, high-performance implantable device for interfacing with the brain. The key facts: Neuralink’s device has over 3,000 electrodes per array, an order …

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