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TL;DR: A 2026 systematic review and meta-analysis in Neurological Sciences found that ketogenic diet (KD), a very-low-carbohydrate diet designed to raise ketone fuel use, looked feasible and generally safe as an add-on strategy in glioblastoma (GBM), but the s…
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TL;DR: A 2026 review in Neuropsychiatric Disease and Treatment argued that electroacupuncture (EA), acupuncture delivered with small electrical stimulation, has depression-related mechanism evidence, but clinical trials need biomarker-guided patient groups, st…
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TL;DR: A 2026 paper in Neuropsychopharmacology argued that cannabidiol (CBD), a non-intoxicating cannabis compound, has plausible psychiatric and neurological uses, but clinical claims need standardized products, exposure tracking, and safety monitoring before…
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Major depressive disorder (MDD) is a global health crisis affecting over 300 million people. While available antidepressants help some patients, treatment is far from satisfactory for many. Exciting research into rapid-acting agents like ketamine and psilocybi…
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The European Medicines Agency (EMA) has updated its guidance on clinical trials for new depression treatments, with the goals of harmonizing standards across the EU and facilitating development of improved therapies. Key Facts: Depression is a highly disabling…
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Kava kava, an herbal supplement made from the root of Piper methysticum, has gained popularity as an alternative treatment for anxiety and insomnia. A recent systematic review and meta-analysis re-examined kava kava’s effectiveness and safety for anxiety disor…
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Fecal microbiota transplantation (FMT) shows potential as an effective new treatment for major depressive disorder (MDD). Key facts: FMT aims to restore a healthy gut microbiome which is thought to impact mood and mental health. Studies show links between gut…
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Long COVID affects millions globally, causing debilitating symptoms that can persist for months or years. Experts are calling for urgent clinical trials to find treatments. Key Facts: Long COVID can cause fatigue, brain fog, muscle weakness, sleep disturbances…
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The novel combination drug dextromethorphan-bupropion (Auvelity) was recently approved by the FDA as an oral antidepressant that works rapidly to treat major depressive disorder in adults. This new medication represents an exciting development for depression t…
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Post-traumatic stress disorder (PTSD) continues to afflict millions worldwide, necessitating more effective therapeutic options. Key Facts: PTSD involves dysfunctional fear processing and altered threat perception. Current treatments fail to comprehensively ad…
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