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TL;DR: A 2026 meta-analysis in Dialogues in Clinical Neuroscience pooled whole-brain functional MRI studies and found that anxious major depressive disorder (anxious MDD, depression with prominent anxiety symptoms) showed different brain-activity patterns from…
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TL;DR: A 2026 systematic review and meta-analysis posted as a medRxiv preprint found that mindfulness-based programs were linked to a small improvement in executive function, meaning inhibition, working memory, and flexible thinking, across 13 youth trials. Ke…
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TL;DR: A 2026 meta-analysis in European Journal of Psychotraumatology found that trauma cues increased substance craving in trauma-exposed people who use substances, and the strongest pathway ran through cue-triggered negative affect. Key Findings 32 studies:…
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TL;DR: A 2026 systematic review and meta-analysis posted to medRxiv found that gamma-frequency non-invasive brain stimulation was linked to symptom improvement in schizophrenia and depressive-symptom reduction in major depressive disorder, but the evidence was…
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TL;DR: A 2026 systematic review and meta-analysis in Acta Neuropsychiatrica found no clear evidence that parenteral clomipramine is better than oral clomipramine for depression or obsessive-compulsive disorder, with low or very low certainty across the main ra…
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TL;DR: A 2026 Psychological Medicine meta-analysis of 109 studies linked parental severe mental illness, especially schizophrenia and bipolar disorder, to lower cognitive performance in offspring across IQ, language, memory, executive function, and general cog…
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TL;DR: A 2026 systematic review and meta-analysis in Drug and Alcohol Review estimated high adolescent substance-use exposure in South Africa, with lifetime alcohol use at 35.09%, tobacco at 25.47%, and cannabis at 10.47% across community and school-based stud…
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TL;DR: A 2026 systematic review and meta-analysis in Neuropsychopharmacology found that dopamine D2-like receptor activation suppressed glucose-stimulated insulin secretion (GSIS), insulin release after high glucose, in animal pancreatic cells, suggesting one…
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TL;DR: A 2026 systematic review in Journal of Clinical Sleep Medicine found that cognitive behavioral therapy for insomnia (CBT-I), a structured behavioral sleep treatment, plus sleep medication improved chronic insomnia more than medication alone, but adding…
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How Often Trauma-Exposed Kids Develop PTSD Now TL;DR: An updated meta-analysis of 95 studies found that about 1 in 5 trauma-exposed children met DSM-IV PTSD criteria and about 1 in 8 met DSM-5 criteria, with the highest rates in girls and in youth exposed to i…
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