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TL;DR: A 2026 medRxiv preprint applied the AT(N) framework, an Alzheimer’s disease biomarker system for amyloid, tau, and neurodegeneration, to 84 older adults with focal epilepsy and found that only 32.1% had normal blood biomarkers, while early-onset epileps…
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TL;DR: A 2026 study in O&G Open found that cannabis exposure 2–7 years after a first pregnancy was not associated with incident hypertension after adjustment in the nuMoM2b Heart Health Study. Key Findings No adjusted hypertension association: Cannabis exposur…
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TL;DR: A 2026 BMC Medicine study of UK Biobank adults linked adversity in both childhood and adulthood to higher frailty, older metabolomic age profiles, lower grip strength, and some telomere differences, with the clearest associations in people reporting mul…
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TL;DR: A 2026 study in Nature Communications found that self-administered finger-prick blood tests for phosphorylated tau 217 (p-tau217), an Alzheimer’s tau marker, and glial fibrillary acidic protein (GFAP), an astrocyte-injury marker, correlated with cogniti…
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TL;DR: A 2026 article-in-press study in Alzheimer’s Research & Therapy found that olfactory-region MRI radiomics, a method that turns brain scans into quantitative texture and shape features, linked blood pTau217, a tau-related Alzheimer’s disease biomarker, w…
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TL;DR: A 2026 study in the Journal of the American Heart Association followed 1,882 stroke-free women from the Framingham Heart Study for a median of 18 years and found that having three or more live births was associated with a reduced risk of clinical stroke…
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TL;DR: A 2026 study in JAMA Network Open analyzed Medicare claims for adults 66+ from 2008 to 2021 and found that cognition-altering medications — antipsychotics, benzodiazepines, hypnotics, anticholinergics — were disproportionately initiated in emergency roo…
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TL;DR: A 2026 medRxiv preprint tested SimulAD, an Alzheimer’s disease progression simulator, and reported that it reproduced mean amyloid-clearance results within 5% error across six major phase III anti-amyloid trials while also separating positive trials fro…
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TL;DR: A 2026 study in JAMA Network Open tracked 1,338 older adults from the Rush Memory and Aging Project for up to 19 years using objective wrist-actigraphy and found that each additional hour of daytime napping per day was linked to ~13% higher mortality, e…
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TL;DR: A 2026 study in The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences measured a monocyte-specific DNA methylation clock (MonoDNAmAge) in 440 women with and without HIV, and found that accelerated monocyte epigenetic aging was…
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