Clonidine for Insomnia & Sleep in Chronic Pain Patients: More Effective Than Zopiclone

A new study published in the Journal of Clinical Sleep Medicine has found that the medication clonidine is more effective and safer than zopiclone for treating insomnia in people with chronic pain. Key findings: Clonidine provided better pain relief than zopiclone. Clonidine helped patients fall asleep faster. Patients felt more rested after taking clonidine compared …

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Modafinil & Serotonin Receptors Influence Gambling Behaviors Like “Loss Chasing”

Gambling is a complex behavior influenced by multiple factors in the brain. New research in mice provides insight into the neurobiology underlying key aspects of gambling such as making the initial decision to gamble and persistently chasing losses. Key Facts: Mice exhibit typical gambling behaviors like choosing to gamble more when odds of winning are …

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Palmitoylethanolamide (PEA) Benefits: Pain, Inflammation, Neuroprotective Effects

Palmitoylethanolamide (PEA) is a naturally occurring molecule that has been shown to have anti-inflammatory, analgesic, and neuroprotective effects in the body and brain. Key Facts: PEA is produced naturally in the body and is also found in many foods like egg yolks, coffee, and soy. It activates PPAR-alpha receptors which regulate inflammation, pain perception, and …

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Cannabis Hyperemesis Syndrome: Causes, Symptoms, Treatments

Cannabis hyperemesis syndrome (CHS) is a newly recognized condition causing severe nausea and vomiting in long-term cannabis users. Key facts about CHS: Repeated, uncontrollable vomiting is the main symptom Occurs in long-term heavy cannabis users Exact cause is unknown, but likely involves cannabis effects on brain receptors Stopping cannabis use is the only definitive cure …

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Probiotics & Antioxidants: L. Rhamnosus & NAC Reduces Binge Drinking Alcohol

Researchers have identified a powerful combination of drugs that may help treat alcoholism by reducing cravings and blocking relapse. The dual treatment virtually wiped out binge drinking and heavy drinking in an animal model of alcohol addiction. Key Facts: Rats treated with both a probiotic and antioxidants showed a dramatic 90% decrease in relapse-like binge …

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Delta-8-THC Side Effects & Adverse Reactions: Reported User Experiences

A new study looked at the side effects people report from using delta-8-THC products and found that most match the side effects seen with regular cannabis. This suggests delta-8-THC acts on the brain in a similar way as the main psychoactive compound in cannabis, delta-9-THC. Key Facts: Delta-8-THC is a compound derived from hemp that …

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Cannabidiol (CBD) Benefits for the Brain: Therapeutic Potential in Psychiatric Conditions

Cannabidiol (CBD) has emerged as a promising therapeutic agent for a variety of mental health conditions. Here’s a quick rundown of the key facts: CBD is a non-intoxicating compound derived from the cannabis plant It has antipsychotic, anti-anxiety, and potential antidepressant effects CBD shows promise for schizophrenia, cannabis addiction, anxiety disorders, autism symptoms, and more …

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New Study Finds High Pesticide Levels in Illegal Cannabis in Canada vs. Legal Products

A new Canadian study reveals that illicit cannabis contains concerning levels of pesticides, while legal cannabis products meet health safety standards. Key Facts: The study tested 327 different pesticides in legal and illegal dried cannabis samples from across Canada. 92% of illegal samples contained pesticides, compared to just 6% of legal samples. Illegal cannabis contained …

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MDMA Assisted Therapy for Alcohol Abuse & PTSD

A new study provides preliminary evidence that MDMA-assisted therapy may help reduce alcohol use in people with severe PTSD. Key facts: MDMA-assisted therapy was tested in a phase 3 clinical trial for treating severe PTSD. Participants were allowed to have mild alcohol or cannabis use disorder. Compared to placebo therapy, MDMA therapy led to greater …

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NSI-189 for Depression & Cognitive Enhancement via Neurogenesis & BDNF

Depression and cognitive deficits are common health issues that impact millions of people. Scientists are testing a new drug, NSI-189, to see if it can help treat depression and improve thinking ability. Early research shows promise that NSI-189 may be able to grow new brain cells and connections, which could potentially treat depression and boost …

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