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FGF21 Hindbrain Neurons Controlled Protein Hunger TL;DR: During protein restriction, liver-derived FGF21 acted through glutamatergic beta-klotho neurons in the nucleus of the solitary tract to change food intake, food choice, and energy expenditure in mice. Ke…
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Early Stress Rewired the Gut’s Nerves, Not Just the Brain TL;DR: Early life stress produced lasting gut pain and motility changes through enteric and sympathetic nerve pathways, with pediatric cohort data pointing in the same direction. Key Findings Maternal s…
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Low-Level Drinking Was Not Invisible to the Aging Cortex TL;DR: Even drinking within low-risk guidelines was linked to lower cortical blood flow and thinner cortex when lifetime exposure met advancing age. Key Findings All participants stayed under 60 drinks p…
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Lifetime Cognitive Enrichment Delayed Alzheimer’s Dementia TL;DR: In 1,939 Rush Memory and Aging Project participants, higher lifetime cognitive enrichment was linked to 38% lower Alzheimer’s dementia hazard and about 5 years later dementia onset. Key Findings…
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Mediterranean Diet Linked Mitochondrial Microproteins TL;DR: Mediterranean diet adherence tracked with higher mitochondrial microproteins Humanin and SHMOOSE in older adults, pointing to a possible mitochondrial route for healthy-aging benefits. Key Findings H…
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Hormone Therapy Linked to 44% Improvement in Menopause Mood Symptoms TL;DR: Menopausal hormone therapy tracked with a 44.59% improvement in mood-symptom scores after about 107 days, across both peri- and postmenopausal women — and the gains were broadly simila…
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The Hidden Postpartum Crisis Nobody Screens For: Paternal Depression Peaks at 10-12 Months TL;DR: Fathers experience a protective period early postpartum (depression drops by 26%), but depression and stress surge at months 10-11, creating a 30-36% elevated ris…
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When Depression Threatens Pregnancy: A 34% Elevated Miscarriage Risk TL;DR: Untreated depression increases miscarriage risk by 34% across nearly 9 million women, but antidepressants reduce that risk to 24%—meaning the medication is safer than the disease durin…
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How Parasites Hack Your Gut-Brain Connection TL;DR: Parasitic infections trigger a sophisticated cellular conversation in the gut that signals the brain to stop eating—a protective response that reveals how infection hijacks the gut-brain axis through epitheli…
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Krill Oil vs Fish Oil: Which Omega-3 Source Wins Against Inflammation and Oxidative Stress? TL;DR: Krill oil has a slight edge for inflammation due to astaxanthin, but fish oil wins for raising blood omega-3 levels and long-term cardiovascular outcomes. Fish o…
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