Brain Tumors Linked to Psychiatric Symptoms in ~27% of Patients

Brain tumors can take a major toll on mental health. New research provides important insights into the psychiatric symptoms that often accompany these devastating diseases. Key Facts: Around 27% of brain tumor patients experience psychiatric symptoms like depression and anxiety. These frequently arise before diagnosis. Depressive symptoms are most common, affecting 24% of brain tumor …

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Fecal Microbiota Transplantation (FMT) for Depression Treatment: Targeting the Gut-Brain Axis

Fecal microbiota transplantation (FMT) shows potential as an effective new treatment for major depressive disorder (MDD). Key facts: FMT aims to restore a healthy gut microbiome which is thought to impact mood and mental health. Studies show links between gut microbiome abnormalities and depression. FMT has successfully treated depression symptoms in animal models. A few …

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High Galectin-1 & Galectin-3 in Autism Spectrum Disorder (ASD): Inflammation Markers

Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by social communication deficits and repetitive behaviors. The causes are complex, involving genetic and environmental factors that affect brain development. Growing evidence implicates immune system abnormalities and neuroinflammation in ASD. Galectin-1 and galectin-3 are proteins that regulate immune responses and inflammation. A new study found significantly …

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Low Neuregulin-1 (NRG-1) Linked to Obesity & Depression

A new case-control study reveals an association between obesity, depression, and decreased levels of the protein neuregulin-1 (NRG-1). The research suggests NRG-1 may serve as a biomarker linking depression and obesity. Key facts: Depressive symptoms were more common in obese individuals compared to normal weight controls. After bariatric surgery, most obese patients saw an improvement …

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Antipsychotics & Gray Matter Loss in Chronic Schizophrenia

Schizophrenia is a severe mental illness characterized by hallucinations, delusions, disorganized thinking and behavior. While antipsychotic medications can help manage symptoms, their long-term effects on brain structure are not fully understood. A new study provides important insights into how long-term antipsychotic treatment may impact gray matter in chronic schizophrenia. Key Facts: Both treated and untreated …

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Antipsychotics & High Prolactin Levels: Which Drugs Cause Hyperprolactinemia Most Often?

Antipsychotic medications are commonly used to treat psychotic disorders like schizophrenia and bipolar disorder. However, these drugs often cause side effects like elevated prolactin levels, which can negatively impact long-term health. A new study analyzed medical records to compare prolactin levels between patients taking different antipsychotics. It found risperidone and amisulpride caused the greatest prolactin …

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Minocycline Adjunct Treatment for Depression via Immune-Inflammation Effects

Major depressive disorder (MDD) is a highly prevalent and debilitating condition. Novel treatment approaches are needed, especially for individuals with treatment-resistant depression. This study investigated the effects of adjunctive minocycline on immune-inflammatory biomarkers and clinical outcomes in MDD. Key Highlights: Minocycline is a broad-spectrum antibiotic with anti-inflammatory, immunomodulatory and neuroprotective properties. It shows promise as …

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Fluoride in Tap Water: History, Dental Benefits, Health Risks, Controversy

Fluoride has revolutionized dentistry with its ability to prevent tooth decay, but concerns remain about potential adverse health effects from over-exposure. Key Facts: Fluoride was discovered in 1901 to cause brown stains on teeth, later found to make teeth resistant to decay Grand Rapids, Michigan became the first city to fluoridate drinking water in 1945, …

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Top Drugs & Medications that Cause Weight Gain: Worst Offending Pharmaceuticals (2012-2021)

A new study published in Pharmazie takes a close look at adverse event reports related to drug-induced weight gain submitted to the FDA over the past 10 years. The retrospective analysis provides insight into the drugs most commonly associated with weight gain side effects. Key findings include: From 2012 to 2021, 137,370 reports of drug-induced …

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