EXPLORE THE SCIENCE
TL;DR: A 2026 human microbiome and intervention study in Nature Communications found that coffee drinkers showed distinct gut microbiome composition and lower several microbial metabolites, while caffeinated and decaffeinated coffee shifted stress and mood mea…
Read article
TL;DR: A 2026 rat study in Neuropsychopharmacology found that chemogenetically inhibiting a prelimbic cortex to nucleus accumbens core pathway blocked cue-triggered cocaine seeking after cocaine alone, but did not block relapse-like behavior after sequential c…
Read article
TL;DR: A 2026 preprint in medRxiv trained machine-learning models on Danish electronic health records and found that an XGBoost model predicted clozapine initiation within 365 days with an AUROC of 0.81 in patients with schizophrenia or schizoaffective disorde…
Read article
TL;DR: A 2026 study in The British Journal of Psychiatry found that people with anxiety disorders showed hyper-scanning during neutral image viewing and hyper-pursuit during moving-dot tracking, suggesting that eye-tracking could capture measurable patterns of…
Read article
TL;DR: A 2026 randomized feasibility trial in JMIR Mental Health found both a structured AI therapy chatbot and ChatGPT reduced PHQ-9 depression scores versus assessment-only control, but neither AI condition improved anxiety significantly or beat the other. K…
Read article
TL;DR: A 2026 systematic review and meta-analysis in Drug and Alcohol Review estimated high adolescent substance-use exposure in South Africa, with lifetime alcohol use at 35.09%, tobacco at 25.47%, and cannabis at 10.47% across community and school-based stud…
Read article
TL;DR: A 2026 study in Neuropsychopharmacology found that reward uncertainty, measured with functional MRI (fMRI), a brain-scan method, engaged different adolescent brain networks during waiting for a possible reward versus learning the outcome, with anxiety a…
Read article
TL;DR: A 2026 study in The British Journal of Psychiatry found that serious mental illness labels shifted often in real-world psychiatric records: 64% of patients with schizophrenia, bipolar disorder, or severe major depression received multiple diagnoses over…
Read article
TL;DR: A 2025 study in Communications Biology found that a week-long mind-body retreat shifted brain-network, plasma-protein, metabolomic, and cell-growth measures, but the uncontrolled design keeps the result exploratory. Key Findings Healthy retreat attendee…
Read article
TL;DR: A 2026 preprint birth-cohort study in medRxiv found that 91.1% of children had experienced violence by age 8, while age-8 violence exposure was associated with higher internalizing, externalizing, total problem scores, and disorder odds. Key Findings Ev…
Read article