TLDR: Occasional drinking may help reduce the risk of major depression, but frequent drinking worsens it. Highlights: Occasional alcohol consumption is linked to a lower risk of major depression. Frequent alcohol intake increases the risk of major depression. The risk increase from frequent drinking persists even when different types of alcohol are considered. The impact …
TLDR: Omega-3 supplementation shows potential for reducing anxiety symptoms, with the most significant improvement at a dose of 2 grams per day. Highlights: Dose-Dependent Effect: Each 1 gram per day of omega-3 supplementation led to a moderate decrease in anxiety symptoms, with the greatest improvement observed at 2 grams per day. Analysis: The meta-analysis included …
TLDR: Quercetin-based alginate nanogels loaded with brain-derived neurotrophic factor (BDNF) can effectively cross the blood-brain barrier via intranasal delivery, providing a promising treatment for depressive disorders. Highlights: Nanogels: Quercetin nanogels protect BDNF from oxidative damage, exhibit rapid brain distribution, and significantly enhance bioavailability compared to oral administration. Efficacy: BDNF-Quercetin nanogels delivered via intranasal route show …
TLDR: A study in the UK found that severe COVID anxiety tends to decrease over 6 months from onset, both organically and with the help of CBT for Health Anxiety (CBT-HA), though many individuals still experience significant anxiety and poor social functioning, with health anxiety being a key factor that can be effectively targeted with …
TLDR: Esketamine nasal spray, combined with standard antidepressant therapy, significantly improves remission rates and reduces time to remission in adults with major depressive disorder (MDD) and acute suicidality compared to standard care alone. Highlights: Remission Rates: Patients treated with esketamine plus standard of care had higher remission rates than those treated with placebo plus standard …
TLDR: A case study reveals a 70-year-old woman developed erotomanic delusions and attempted suicide following online romance fraud. Highlights: 70-year-old woman with persistent depressive disorder. Victim of online romance fraud involving a renowned musician’s image. Developed erotomanic delusions and attempted suicide. Treatment included antidepressants, low-dose risperidone, and therapy. Significant symptom remission after four weeks of …
TLDR: A study found that veterinarians frequently euthanizing animals have higher rates of serious suicidal thoughts and are more likely to support euthanasia for humans. Working with companion animals is associated with positive attitudes towards human euthanasia. Highlights: Data from over 2,500 veterinarians in Norway. 55% of veterinarians support euthanasia for humans with terminal illness. …
TLDR: A recent study explored the potential causal relationship between atopic dermatitis (AD) a.k.a. eczema and various psychiatric disorders – finding bidirectional links. Highlights: Data from over 860,000 individuals were analyzed Atopic dermatitis (eczema) increased risk of ADHD & ASD ADHD, anorexia nervosa (AN), bipolar disorder (BD) increased the risk of developing atopic dermatitis (eczema) …
Those with personality disorders face an elevated risk of suicidal thoughts, attempts, and deaths. Factors like childhood trauma and substance use issues may partially explain this vulnerability. While treatments like dialectical behavior therapy show promise for prevention, more research is still needed. Key Facts: 17 of 24 studies found personality disorders tied significantly to suicidal …
Antidepressant use has risen steadily for 30 years. Over 10% of adults in England now take them long-term, but evidence suggests up to half lack clear medical justification to continue. Patients and doctors are reluctant to stop treatment due to fears of relapse and withdrawal effects. Research indicates more proactive treatment review, slower drug tapering …
