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TL;DR: A 2026 study in Implementation Science Communications found that high-performing HEALing Communities Study coalitions used representative membership, shared goals, data support, and communications campaigns to strengthen opioid-use-disorder service impl…
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TL;DR: A 2026 Journal of Global Health analysis of Global Burden of Disease 2021 data estimated that 162.86 million people had substance use disorders in 2021, with age-standardized rates down since 1990 but major inequality across sex, age, region, and develo…
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TL;DR: A 2026 randomized controlled study in Pakistan Journal of Pharmaceutical Sciences found that adding 20 Hz repetitive transcranial magnetic stimulation (rTMS) to risperidone was linked with lower cognitive-factor and aggression scores after 4 weeks in sc…
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TL;DR: A 2026 study in Behavior Genetics found that combining major depressive disorder and alcohol use disorder polygenic scores improved prediction of their comorbidity in 7,965 Add Health participants, but added little for either condition alone. Key Findin…
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TL;DR: A 2026 randomized pilot study in JMIR Formative Research found that one brief yoga session did not significantly change salivary cortisol compared with quiet sitting, but it did raise heart rate during the active movement phase. Key Findings Yoga pilot…
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TL;DR: A 2026 meta-analysis in BMC Psychiatry found a moderate cross-sectional association between body dysmorphic disorder symptoms and perfectionism across 34 studies and 13,107 participants. Key Findings 34-study meta-analysis: The review pooled 34 studies…
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TL;DR: A 2026 Nature Neuroscience study used cross-species functional MRI (fMRI) connectivity to identify hypoconnectivity and hyperconnectivity autism subtypes linked to different synaptic and immune-related biological pathways. Key Findings 20 mouse models:…
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TL;DR: A 2025 study in Journal of the American Chemical Society used photochemistry to turn amino-acid-linked tryptamines into azocinoindoles that activated serotonin 5-HT2A signaling while suppressing the mouse head-twitch response. Key Findings C4 indole rou…
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TL;DR: A 2026 study in Biological Psychiatry: Global Open Science linked serious physical injury to recurrent major depression and found that injury-related DNA methylation patterns differed by depression status, with oxytocin, GABA, and synaptic-plasticity pa…
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TL;DR: A 2026 review in CNS Drugs argues that seletracetam, an unapproved SV2A-targeting antiseizure drug, may deserve renewed development as a low-volume intranasal non-benzodiazepine rescue treatment for acute repetitive seizures. Key Findings SV2A racetam:…
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