Adult Stressor Severity Linked to Higher Hair Cortisol in One Study

Adult Stressor Severity Linked to Higher Hair Cortisol in One Study

TL;DR: A 2026 study in Comprehensive Psychoneuroendocrinology found that adulthood stressor severity was linked to higher hair cortisol in a longitudinal sample, while early-life stress, recent stress, daily phone-based stress reports, and the cortisol/DHEA ratio did not show consistent associations. Key Findings 2 aligned samples were tested: Study I included 79 adults, and Study II …

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ADHD and Depression Diagnoses Rose in Children With Intellectual Disability

ADHD and Depression Diagnoses Rose in Children With Intellectual Disability

TL;DR: A 2026 nationwide study in Journal of Korean Medical Science found that among South Korean children and adolescents with intellectual disability, diagnosed ADHD increased from 30.23% in 2012 to 41.77% in 2021, while diagnosed depression increased from 10.46% to 19.37%. Key Findings Population: Researchers analyzed South Korean national health-insurance records for children and adolescents …

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Brain Iron Deficiency Sensitized a Dopamine-Opioid Restless Legs Pathway

Brain Iron Deficiency Sensitized a Dopamine-Opioid Restless Legs Pathway

TL;DR: A 2026 mouse study in Neuropsychopharmacology found that brain iron deficiency made an opioid-responsive striatal pathway unusually sensitive to D1 dopamine receptor stimulation, pointing to a possible circuit mechanism for restless legs syndrome and opioid-withdrawal restlessness. Key Findings Iron-deficient mouse model: Researchers used a low-iron diet to create brain iron deficiency (BID), a rodent …

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Resting-State EEG Network Markers Distinguished Epilepsy From Functional Seizures

Resting-State EEG Network Markers Distinguished Epilepsy From Functional Seizures

TL;DR: A 2026 medRxiv preprint found that multivariate resting-state electroencephalography (EEG) network markers separated non-lesional epilepsy from functional/dissociative seizures above chance, but the best model was stronger at identifying epilepsy than at identifying functional/dissociative seizures. Key Findings 148 suspected seizure cases: Researchers analyzed medication-free, visually normal, eyes-closed EEG recordings from 75 people later diagnosed with …

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Occult Sleep Apnea Was Common in Hodgkin Lymphoma Survivors After Mantle Radiation

Occult Sleep Apnea Was Common in Hodgkin Lymphoma Survivors After Mantle Radiation

TL;DR: A 2026 study in Journal of Clinical Sleep Medicine found that 36 of 42 Hodgkin lymphoma survivors tested after mantle radiation therapy had obstructive sleep apnea (OSA), despite mostly normal BMIs and slender necks — an under-recognized phenotype linked to dropped head syndrome. Key Findings 182 long-term HL survivors: All had received mantle radiation …

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New Psychoactive Stimulants and Hallucinogens Found in 70 Fatal Poisonings

New Psychoactive Stimulants and Hallucinogens Found in 70 Fatal Poisonings

TL;DR: A 2026 study in Drug and Alcohol Dependence Reports found 70 known Australian fatal poisonings involving new psychoactive stimulants and hallucinogens (NPSH), a category of newer stimulant- or hallucinogen-like drugs that often appeared alongside other psychoactive substances. Key Findings Researchers identified 70 fatal drug-toxicity cases in Australia from 2000 to 2025 where NPSH were …

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7-Day Memory Test Found Hidden Forgetting in Multiple Sclerosis

7-Day Memory Test Found Hidden Forgetting in Multiple Sclerosis

TL;DR: A 2026 medRxiv preprint found that adults with multiple sclerosis showed accelerated long-term forgetting (ALF), meaning unusually steep memory loss over days despite normal early recall, on two verbal memory tests. Key Findings The long-delay test was the key contrast: researchers compared 62 adults with multiple sclerosis and 65 matched controls using word-list and …

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Monthly Lecanemab Maintained Alzheimer’s Blood Biomarker Changes After 18 Months

Monthly Lecanemab Maintained Alzheimer's Blood Biomarker Changes After 18 Months

TL;DR: A 2026 study in Alzheimer’s & Dementia: Translational Research & Clinical Interventions used lecanemab pharmacokinetic/pharmacodynamic modeling in early Alzheimer’s disease and found that blood biomarkers worsened after treatment stopped, while monthly maintenance dosing after 18 months was predicted to preserve most p-tau181 and GFAP, an astrocyte-inflammation protein. Key Findings Three plasma biomarkers improved: Lecanemab …

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Misophonia and Hyperacusis Showed Different fMRI Sound-Processing Patterns

Misophonia and Hyperacusis Showed Different fMRI Sound-Processing Patterns

TL;DR: A 2026 study in Cognitive, Affective, & Behavioral Neuroscience used task-based functional MRI (fMRI), a brain-scan method that tracks blood-oxygen changes during a task, to show that misophonia and hyperacusis had partly different brain connectivity patterns during unpleasant sound processing. Key Findings 91 young adults were analyzed after 1 participant was excluded for excessive …

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Smartphone Migraine Study Captured Daily Brain Fog and Symptom Burden

Smartphone Migraine Study Captured Daily Brain Fog and Symptom Burden

TL;DR: A 2026 medRxiv preprint enrolled 177 adults with migraine in a 30-day smartphone study and found that daily cognition and symptom check-ins were feasible, with 3,688 completed assessments and higher baseline burden in chronic migraine. Key Findings Migraine cohort: The MIND study followed 177 adults with migraine using once-daily smartphone surveys and brief mobile …

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