Gamma Neuromodulation Linked to Schizophrenia and Depression Symptom Gains

Gamma Neuromodulation Linked to Schizophrenia and Depression Symptom Gains

TL;DR: A 2026 systematic review and meta-analysis posted to medRxiv found that gamma-frequency non-invasive brain stimulation was linked to symptom improvement in schizophrenia and depressive-symptom reduction in major depressive disorder, but the evidence was heterogeneous and still preprint-level. Key Findings 56 controlled studies were included across schizophrenia, major depressive disorder, bipolar disorder, and autism spectrum …

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COVID Neurocognitive Recovery Improved After Alpha/Delta and Omicron

COVID Neurocognitive Recovery Improved After Alpha/Delta and Omicron

TL;DR: A 2026 study in Neuropsychiatric Disease and Treatment followed 55 adults after mild-to-moderate COVID-19 and found that neurocognitive test performance improved over time after both Alpha/Delta-era and Omicron-era infections. Key Findings 55-person longitudinal sample: Researchers compared 28 Alpha/Delta-era participants with 27 Omicron-era participants after mild-to-moderate COVID-19. Initial cognitive findings: About half of each group …

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Lithium Loading Dose Plus Quetiapine Reduced Acute Mania More Than Standard Titration

Lithium Loading Dose Plus Quetiapine Reduced Acute Mania More Than Standard Titration

TL;DR: A 2026 randomized single-blind trial in BMC Psychiatry found that a one-day lithium carbonate loading dose plus quetiapine reduced acute manic symptoms in bipolar I disorder more than standard slow-titration lithium plus quetiapine over 14 days. Key Findings 60 inpatients randomized: Adults with bipolar I disorder in acute mania, all meeting DSM-5 criteria and …

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Whole-Body Hyperthermia Activated Blood RNA Pathways in Major Depression

Whole-Body Hyperthermia Activated Blood RNA Pathways in Major Depression

TL;DR: A 2026 study in Brain, Behavior, & Immunity – Health found that whole-body hyperthermia in adults with major depressive disorder triggered a 30-minute whole-blood RNA-seq response dominated by heat-shock genes and immune pathways, including IL-6 production. Key Findings 18 RNA-seq participants: Whole-blood RNA sequencing was available for 9 adults assigned to whole-body hyperthermia and …

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Sleep History Modulated Wake EEG Oscillations Across Development With Distinct ADHD Patterns

Sleep History Modulated Wake EEG Oscillations Across Development With Distinct ADHD Patterns

TL;DR: A 2026 eNeuro study of 163 people ages 3-25 found that sleep history and age shaped waking electroencephalography (EEG) oscillations, while children with ADHD showed distinct sleep-wake EEG patterns. Key Findings Sleep and development interact to shape wake EEG oscillations: The amount of recent sleep or wakefulness produces age-dependent effects on EEG oscillation amplitude …

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Psychopathy Linked to Higher Cortical Surface Area in 804 Incarcerated Men

Psychopathy Linked to Higher Cortical Surface Area in 804 Incarcerated Men

TL;DR: A 2026 study in Biological Psychiatry: Global Open Science linked higher psychopathy in MRI data from 804 incarcerated men to lower empathic concern and broader cortical surface area, while empathy scores themselves were not directly tied to cortical thickness or surface area. Key Findings The sample was large for prison MRI research: the study …

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Year-Long Aerobic Exercise Lowered Long-Term Cortisol in Midlife Adults: First Randomized Trial Mapping Cause and Effect

Year-Long Aerobic Exercise Lowered Long-Term Cortisol in Midlife Adults: First Randomized Trial Mapping Cause and Effect

TL;DR: A 2026 randomized clinical trial in the Journal of Sport and Health Science assigned 130 midlife adults to 150 minutes/week aerobic exercise or no-exercise control for 1 year and found sustained lower long-term cortisol in the exercise group. Key Findings Year-long randomized trial in 130 midlife adults: Participants aged 26 to 58 were randomly …

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Right OFC rTMS Improved Visuospatial Memory in First-Episode Schizophrenia

Right OFC rTMS Improved Visuospatial Memory in First-Episode Schizophrenia

TL;DR: A 2026 randomized study in Psychological Medicine found that right orbitofrontal cortex repetitive transcranial magnetic stimulation (rTMS), a noninvasive brain-stimulation method, improved visuospatial memory on the Brief Visuospatial Memory Test-Revised (BVMT) in people with first-episode schizophrenia. Key Findings The analysis included 90 patients: Researchers studied 48 people assigned to active rTMS and 42 assigned …

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Daughter-Led Humor Linked to More Open Sex Communication With Mothers

Daughter-Led Humor Linked to More Open Sex Communication With Mothers

TL;DR: A 2026 study in The Journal of Sex Research found that teenage daughters’ own humor during sexuality conversations was linked to more open mother-daughter communication and higher sexual well-being, while mothers’ humor was linked to less openness from daughters. Key Findings 98 mother-daughter pairs: Researchers analyzed confidential survey data from Israeli mothers and teenage …

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Rats Outperformed Humans in 2-Second Temporal Error Monitoring Task

Rats Outperformed Humans in 2-Second Temporal Error Monitoring Task

TL;DR: A 2026 iScience study found that both humans and rats could report their own timing errors in a 2-second task, but rats made more accurate error-based choices than humans. Key Findings Matched timing task: Researchers compared 34 adults with 16 male Sprague-Dawley rats in a similar 2-second time-production task. Both species monitored errors: Humans …

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