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TL;DR: A 2026 study protocol in Trials describes COSTS, a randomized trial that will compare cognitive behavioral therapy for insomnia (CBT-I) with standard cognitive behavioral therapy (CBT) in 60 people with treatment-resistant schizophrenia and persistent s…
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TL;DR: A 2026 systematic review and meta-analysis in Psychogeriatrics linked loneliness with Alzheimer’s disease and several forms of suicidal behavior, with especially strong shared correlations for hopelessness, insomnia, entrapment, and stress. Key Findings…
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TL;DR: A 2026 network analysis study in European Archives of Psychiatry and Clinical Neuroscience found that insomnia was present in 18.3% and childhood trauma in 49.5% of patients, while daytime dysfunction and sleep-related distress were central nodes, while…
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TL;DR: A 2025 randomized trial in Scandinavian Journal of Primary Health Care found that a self-help book based on cognitive behavioral therapy for insomnia (CBT-I), a structured non-drug insomnia treatment, reduced daily hypnotic sleep-medication use and anxi…
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Cannabinoids Had Weak Evidence for Mental Disorders TL;DR: A Lancet Psychiatry review of randomized trials found little support for routine cannabinoid treatment in common mental disorders, despite possible weak signals in a few narrower conditions. Key Findin…
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The Brain That Won’t Shut Down: How Fragmented REM Sleep Breeds Depression TL;DR: Chronic insomnia fragments REM sleep through persistent hyperarousal, preventing emotional memory consolidation and creating a vicious cycle that breeds depression—but cognitive-…
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Insomnia and daytime napping are causally associated with an increased risk of major depressive disorder (MDD), while sleep duration influences the risk of schizophrenia and attention-deficit/hyperactivity disorder (ADHD). Highlights: Major Depressive Disorder…
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Different psychiatric conditions exhibit varied sleep problems, with insomnia and fatigue being the most common issues. Highlights: Worst Sleep Profiles: Traits related to affect disorders, generalized anxiety, and ADHD show the worst sleep problems, including…
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Antidepressant withdrawal symptoms occur in about one-third of patients stopping antidepressants, with severe symptoms in about 3% of cases – according to a new Lancet Psychiatry review. Highlights: Incidence of Symptoms: Approximately 31% of patients experien…
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Insomnia is a common sleep disorder affecting up to 15% of adults. While sedative medications are often prescribed, their long-term use can lead to dependence. As an alternative, antidepressants are widely used in clinical practice despite limited evidence sup…
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