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TL;DR: A 2026 preprint in medRxiv found that the ADAS-Cog-13 cognitive scale detected impairment in older adults with focal epilepsy, but a cutoff of 15 had only modest diagnostic accuracy against an epilepsy-specific neuropsychological standard. Key Findings…
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TL;DR: A 2026 medRxiv preprint found that older adults with Montreal Cognitive Assessment (MoCA)-defined mild cognitive impairment had less coordinated pulse-wave responses during a cognitive challenge than cognitively intact older adults. Key Findings Communi…
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TL;DR: A 2026 study in PLOS One found that people with Parkinson’s disease made more silent pauses while reading aloud, especially when sentences were longer or syntactically more complex. Key Findings Reading task compared 71 adults: Researchers compared 32 p…
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TL;DR: A 2026 medRxiv preprint found that a composite cerebral small vessel disease (cCSVD) score from routine T1 MRI predicted 3-month cognitive recovery after stroke better than any single small-vessel marker in a 65-person cohort. Key Findings Recovery wind…
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TL;DR: A 2026 BMC Psychiatry study found that antipsychotic dose was not associated with Montreal Cognitive Assessment (MoCA), a brief cognitive screening test, in clinically stable schizophrenia patients under 40, while higher symptom scores and longer illnes…
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TL;DR: A 2026 study in Journal of Medical Case Reports described a 71-year-old breast-cancer survivor whose Montreal Cognitive Assessment (MoCA), a cognitive screening test, increased from 16 to 20 and whose 15-item Geriatric Depression Scale (GDS-15), a depre…
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TL;DR: A 2026 medRxiv preprint used total-body tau PET in Alzheimer’s disease and found stronger brain-organ network synchrony, a pattern that tracked cognitive impairment through cortical tau burden and MRI markers of glymphatic dysfunction. Key Findings Smal…
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TL;DR: A 2026 medRxiv preprint used quantitative multi-parametric MRI mapping in 245 BeLOVE participants and found that white matter hyperintensities had lower MTsat and R1 plus higher proton density, with nearby normal-appearing white matter also showing micr…
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TL;DR: A 2026 medRxiv preprint applied the AT(N) framework, an Alzheimer’s disease biomarker system for amyloid, tau, and neurodegeneration, to 84 older adults with focal epilepsy and found that only 32.1% had normal blood biomarkers, while early-onset epileps…
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