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TL;DR: A 2026 Nature Communications study found that small sets of amino-acid changes could swap ligand preference between beta2 adrenergic and D1 dopamine receptors, showing that receptor selectivity depends on both the binding pocket and surrounding structur…
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TL;DR: A 2026 preprint in medRxiv found that a parent-cocreated sensory-reactivity outcome set captured anxiety, mood, sleep, fatigue, cognition, and peer-relationship changes during bumetanide treatment in children and adolescents with neurodevelopmental diso…
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TL;DR: A 2026 Scientific Reports study reported that machine learning models classified brain tumor MRI images across four categories with high internal accuracy, led by a convolutional neural network at 99.29% on a single public dataset. Key Findings 7,023 MR…
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TL;DR: A 2026 qualitative study in iScience found that a 10-week Arts on Prescription program helped unemployed young adults with anxiety, depression, or stress report better mood, stronger routines, and less isolation, but some activities also caused stress,…
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TL;DR: A 2026 meta-analysis in Dialogues in Clinical Neuroscience pooled whole-brain functional MRI studies and found that anxious major depressive disorder (anxious MDD, depression with prominent anxiety symptoms) showed different brain-activity patterns from…
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TL;DR: A 2026 study in Annals of General Psychiatry found that, among 457 adults with recurrent major depressive disorder in Pakistan, escitalopram was the most common single antidepressant and reported side effects varied sharply by drug class. Key Findings C…
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TL;DR: A 2026 narrative review in the Japanese Journal of Radiology reported that Alzheimer’s brain positron emission tomography (PET) imaging has shifted from supportive diagnosis toward treatment selection because amyloid PET is now central to confirming eli…
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TL;DR: A 2026 study in Environmental Science & Technology found that male guppies exposed for 11 days to environmentally relevant amitriptyline, a tricyclic antidepressant detected in waterways, made more spatial-learning errors in a maze while females were la…
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TL;DR: A 2026 medRxiv preprint applied ChatGPT-4o-assisted Bayesian-frequentist hybrid inference to Alzheimer’s single-nucleus RNA-seq data and identified gamma-secretase and HP1 transcription pathways that a no-evidence frequentist setting did not recover. Ke…
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TL;DR: A 2026 medRxiv review found that mental-health AI agents are moving quickly toward large-language-model chatbots, but most systems still rely on text self-report, narrow depression/anxiety/suicide use cases, and offline tests rather than prospective cli…
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