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TL;DR: A 2026 study in Microbiome found that in older adults at metabolic risk, virgin olive oil was linked to better cognitive preservation and richer gut microbiota, while common refined olive oil pointed the other way. Key Findings Metabolic-risk cohort tra…
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TL;DR: A 2026 study in Cell Chemical Biology found that alzheimer’s inflammation may be driven by a specific chemical switch: S-nitrosylation of STING at cysteine 148, which pushed innate immune signaling toward synaptic damage. Key Findings STING carried the…
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TL;DR: A 2026 study in Neurology Open Access found that in 793 dementia-free adults, higher vitamin D levels around age 39 were associated with less tau readout on PET brain imaging about 16 years later, while amyloid beta did not show the same relationship. K…
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TL;DR: A 2026 study in Translational Psychiatry found that three different plasma p-tau217 assays separated Alzheimer’s dementia from controls and frontotemporal degeneration with excellent accuracy, shifting the test from whether the marker works to which pla…
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TL;DR: A 2026 review in Reviews in the Neurosciences argues that chemotherapy-induced peripheral neurotoxicity (CIPN), nerve injury from cancer treatment, can involve central nervous system changes that help explain chronic neuropathic pain and chemotherapy-re…
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TL;DR: A 2026 Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring study found that orbitofrontal and frontoinsular visual rating scales on MRI helped distinguish possible from probable behavioral variant frontotemporal dementia. Key Findings bvF…
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TL;DR: A 2026 study in Nature Communications found that self-administered finger-prick blood tests for phosphorylated tau 217 (p-tau217), an Alzheimer’s tau marker, and glial fibrillary acidic protein (GFAP), an astrocyte-injury marker, correlated with cogniti…
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TL;DR: A 2026 BJPsych Open study found clinically significant anxiety in about 18% of non-demented ALS patients for state anxiety and 14% for trait anxiety, with anxiety scores driven mainly by cognitive-affective depression symptoms rather than motor severity…
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TL;DR: A 2026 medRxiv preprint found that white matter hyperintensity (WMH) burden, the amount of MRI-visible white-matter injury, was greater and progressed faster in amyotrophic lateral sclerosis (ALS), with progression tied to worse motor and cognitive scor…
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TL;DR: A 2026 systematic review and exploratory network meta-analysis of 5 randomized trials in Neurological Sciences found dose-specific ON-medication motor improvements, measured while usual Parkinson’s drugs were active, for some GLP-1 receptor agonists, gl…
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