Psilocybin Increased 6-Month Smoking Abstinence to 40% vs 10% on Nicotine Patch

Psilocybin Increased 6-Month Smoking Abstinence to 40% vs 10% on Nicotine Patch

TL;DR: A 2026 randomized clinical trial in JAMA Network Open found that one supervised 30 mg/70 kg psilocybin dose plus cognitive behavioral therapy produced 40.5% six-month smoking abstinence versus 10.0% with a nicotine patch plus the same therapy. Key Findings 40.5% vs. 10% prolonged abstinence at 6 months: 17 of 42 psilocybin participants stayed biochemically …

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Transgender People Reported More Discrimination and Violence Across Europe

Transgender People Reported More Discrimination and Violence Across Europe

TL;DR: A 2026 study in the International Journal of Transgender Health found that transgender respondents in the 2020 EU LGBTI Survey II reported more discrimination and violence than cisgender lesbian, gay, and bisexual respondents across 30 European countries, with disability and ethnic-minority status linked to larger disparities. Key Findings 138,212 respondents analyzed: the study used …

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5 Music Therapy Sessions Reduced Stress in Psychiatric Inpatients

5 Music Therapy Sessions Reduced Stress in Psychiatric Inpatients

TL;DR: A 2026 randomized trial in PLOS One found that 5 MIDI-assisted group music therapy sessions during psychiatric hospitalization reduced Depression Anxiety Stress Scale-21 (DASS-21) stress scores more than 1 session, while anxiety, depression, life satisfaction, and immediate emotional-response measures did not clearly differ by session frequency. Key Findings Stress fell further: DASS-21 stress showed …

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COPE-A Reduced Youth PTSD Symptoms, But Substance Use Did Not Drop More Than Counseling

COPE-A Reduced Youth PTSD Symptoms, But Substance Use Did Not Drop More Than Counseling

TL;DR: A 2026 randomized trial analysis in European Journal of Psychotraumatology found that COPE-A, an integrated exposure-based therapy for youth with posttraumatic stress disorder (PTSD) and substance use disorder (SUD), reduced PTSD symptoms more than supportive counseling, but substance-use reductions were not significantly stronger than counseling. Key Findings 49 treated participants were analyzed: Youth aged …

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AT(N) Blood Biomarkers Were Often Abnormal in Older Adults With Epilepsy

AT(N) Blood Biomarkers Were Often Abnormal in Older Adults With Epilepsy

TL;DR: A 2026 medRxiv preprint applied the AT(N) framework, an Alzheimer’s disease biomarker system for amyloid, tau, and neurodegeneration, to 84 older adults with focal epilepsy and found that only 32.1% had normal blood biomarkers, while early-onset epilepsy carried higher odds of biomarker abnormality. Key Findings Epilepsy cohort: Researchers analyzed focal epilepsy participants from the …

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Dream Content Reflected Traits and COVID Lockdown Stress

Dream Content Reflected Traits and COVID Lockdown Stress

TL;DR: A 2026 study in Communications Psychology analyzed 1,687 dream reports and 1,679 waking reports, finding that dreams were more visual, spatial, social, bizarre, and emotionally negative than waking experiences. Key Findings 3,366 reports analyzed: the main dataset included 1,687 dream reports and 1,679 waking reports from 207 adults collected between 2020 and 2024. Dreams …

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Sleep-Like Brain Waves Linked ADHD Attention Lapses

Sleep-Like Brain Waves Linked ADHD Attention Lapses

TL;DR: A 2026 study in The Journal of Neuroscience found that adults with ADHD showed more sleep-like brain waves, known as slow waves, while awake, and those brief local sleep states helped explain lapses in attention and vigilance. Key Findings 32 ADHD adults tested: The study compared 32 medication-free adults with ADHD with 31 neurotypical …

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Virgin Olive Oil Linked Gut Microbes to Cognition

Virgin Olive Oil Linked Gut Microbes to Cognition

TL;DR: A 2026 study in Microbiome found that in older adults at metabolic risk, virgin olive oil was linked to better cognitive preservation and richer gut microbiota, while common refined olive oil pointed the other way. Key Findings Metabolic-risk cohort tracked over time: The analysis followed 656 older adults who were 55-75 years old, cognitively …

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TRD Brain Networks Decoupled Structure From Function

TRD Brain Networks Decoupled Structure From Function

TL;DR: A 2026 study in npj Mental Health Research found that a 308-person multimodal MRI study found treatment-resistant depression carried a distinct structure-function decoupling pattern, and machine-learning models separated TRD from non-resistant depression with AUCs up to 0.95. Key Findings 72 TRD patients analyzed: The final sample included 72 patients with treatment-resistant depression, 152 with …

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